Cancer Flashcards
Exam 2
Cancer- who does it effect?
Affects males and females
Affects all ages
Cancer- how is presentation?
Presentation varies from severe/acute to chronic
Cancer: What are clinical features?
Type
Staging
Molecular characteristics
Cancer Epidemiology: What is the leading cause of death worldwide?
Cancer is the leading cause of death worldwide
Cancer EPIDEMIOLOGY: What are the most common types of cancer globally?
Most common types of cancer globally:
Lung,
Breast,
Colorectal,
Stomach
Prostate
Cancer EPIDEMIOLOGY: What can lead to cancer disease patterns?
Carcinogen exposure varies leading to different cancer disease patterns
Cancer prevalence in the US: What percent of cancers are diagnosed in 55+ adults?
What is the greatest incidence of cancers?
78% of all cancers diagnosed in older adults aged 55+ years
Greatest incidence are prostate, breast, and lung
Cancer Epidemiology:
Risk Factors of Cancer: What is the most common risk for cancer?
Most common risk factor for cancer is exposure to a carcinogen
Cancer Epidemiology:
Risk Factors of Cancer: What to know about carcinogens and risk of cancer?
Carcinogens alone are unlikely cancers triggers
Cancer Epidemiology:
What influences cancer development?
Environmental, hormonal, lifestyle factors; infectious disease; medications; immune status; and nutrition
Advanced age and genetic predisposition
Cancer pathophysiology:
Carcinogenesis: What does it begin with?
Begins with carcinogen exposure
Cancer Pathophysiology:
What does carcinogenesis trigger?
Subsequently triggers single or multiple gene mutations
Cancer Pathophysiology:
What happens with mutated cells?
Mutated cells are not detected by the immune system
Cancer Pathophysiology:
What happens with mutated cells that are not detected by the immune system?
Proliferate and progress into cancer
Cancer Pathophysiology:
What are the hallmark characteristics of cancer?
- Uncontrolled cell growth
- Alteration in cell differentiation
Two main categories that cancer cells are divided into:
- Solid Tumors
- Hematological malignancies
What is the reason why cancer cells are able to spread?
Because of the lymphatic system
Cancer: 3 Subcategories of hematological malignancies
- Leukemia
- Lymphoma
- Multiple myeloma