Histopathology 14: Urological Pathology Flashcards
Name 3 benign renal neoplasms
Papillary adenoma
Renal onocytoma
Angiomyolipoma
List 3 types of renal calculi
Calcium oxalate
Magnesium Ammonium phosphate
Uric acid
Infection with which organisms leads to magnesium ammonium phosphate calculi ?
Urease producing organisms - Proteus
What is a stag horn calculus ?
A very large magnesium ammonium phosphate stone
In which syndrome do you get renal Onocytoma ?
Birt-Hogg-Dubé syndrome
Which benign renal neoplasm is seen in tuberous sclerosis ?
Angiomyolipoma
List risk 5 risk factors for renal cell carcinoma ?
Smoking Obesity Long term dialysis Von hippel Lindau syndrome Aromatic amines
List 3 subtypes of renal cell carcinoma ?
clear cell renal cell carcinoma (75%)
Papillary renal cell carcinoma (15%)
Chromophobe renal cell carcinoma (5%)
10% other
Name 1 malignant renal tumour of childhood?
Nephroblastoma (Wilm’s tumour)
Which 3 genetic mutations are commonly associated with Papillary adenoma / carcinoma
Trisomy 7
Trisomy 17
Deletion of Y chromosome
List 3 treatments for benign prostatic hyperplasia (BPH)?
5 alpha reductase inhibitors
Alpha blockers
transurethral resection of the prostate (TURP)
What scoring system is used to predict prognosis of prostatic adenocarcinoma ?
Gleason score
25 year old male presents with a painless testicular lump. He has a history of an undescended testicle and was low birthweight.
What is the most likely neoplastic cause ?
A testicular germ cell tumour
List 5 subtypes of germ cell tumours?
Seminoma Choriocarcinoma Yolk sac tumour Post pubertal teratoma Embryonal carcinoma
Which subtype of testicular germ cell tumours shows a lace-like pattern on histology
Yolk sac tumour
