Chempath 18: Assessment Of Renal Function 1

Question 1

What is considered the best measure of Kidney function ?

Answer 1

GFR

Question 2

List 3 criterias that need to be fulfilled for a marker of clearance to be an accurate representation of GFR ?

Answer 2

• The marker is not bound to serum proteins
• The marker is freely filtered by the glomerulus
• The marker is not secreted or reabsorbed by tubular cells

Question 3

Name an endogenous markers that is measured clinically to estimate GFR ?

Answer 3

Creatinine

Question 4

Apart from haematuria what else can cause a +ve dipstick result for blood ?

Answer 4

Myoglobinuria

Seen in rhabdomyolysis

Question 5

What does the measure SG tell you on the urine dipstick ?

Answer 5

Specific gravity

Its a measure of urine concentration

Question 6

Which marker of multiple myeloma can be detected in the urine ?

Answer 6

Bence jones proteins

Question 7

A 50 year old, known alcoholic, presents generally unwell, seemingly intoxicated, with acute kidney injury. Urine microscopy reveals calcium oxalate Chrystals. What is the diagnosis?

Answer 7

Ethylene glycol poisoning (anti-freeze)

Question 8

List 4 different methods of imaging the renal/urological system ?

Answer 8

Ultrasound KUB
IV Urogram (paediatrics looking for anatomical defects)
CT KUB
MRI KUB

KUB = kidney ureter bladder

Question 9

Which mode of imaging is considered gold standard for identification of kidney stones ?

Answer 9

CT KUB