Hepatocellular carcinoma Flashcards
1
Q
What are the risk factors for heaptocellular carcinoma?
A
Cirrhosis= biggest precipitator
Hep B= main cause worldwide
Hep C= main cause in Europe
Chronic heavy alcohol use
2
Q
What are the features of hepatocellular carcinoma?
A
Abdo distension
RUQ pain
JAundice
Systemic dymptoms
3
Q
What investigations are done for hepatocellular carcinoma?
A
Surveillance US for cirrhosis
CT//MRI
Alpha fetoprotein elevated
Liver biopsy= rare
4
Q
What are the curative management options for hepatocellualr carcinoma?
A
Resection
Transplant
5
Q
What are the management options for hepatocellular carcinoma?
A
Surgery
Chemo
Locally ablative- alcohol injection, radio frequency
Hormonal therapy
6
Q
What is the prognosis for hepatocellular carcinoma?
A
Poor
15% at 5 years
