Colorectal cancer Flashcards
What is the most common type of colorectal cancer?
Adenocarcinoma- 95%
What is the most commonly affected location in colorectal cancer?
Rectum
What are the risk factors in sporadic cases of colorectal cancer?
Age Male Previous adenoma/adenocarcinoma Diet Obesity Sedentary lifestyle Smoking Alcohol
What conditions are associated with colorectal cancer?
HNPCC
FAP
IBD
Coeliac
What is the most common inheritable condition causing colorectal cancer?
HNPCC
What are the signs and symptoms of colorectal cancer?
Asymptomatic Lower GI bleeding Change in bowel habit Acute bowel obstruction Weight loss, anorexia Iron deficiency anaemia Palpable rectal or abdo mass
What screening is done in the general population for colorectal cancer?
FOB test every 2 years from 50-74yo
What high risk groups are offered specific screening?
HNPCC FAB IBD FH PMH
What screening is done for people with HNPCC?
2 yearly colonoscopy from age 25
What are people with HNPCC at esp high risk of?
Right sided colorectal cancers
What is the screening for FAP?
Annual colonoscopy from age 10-12
What is the prevention of colorectal cancer in FAP?
Prophylactic proctocolectomy at 16-25
What is the screening for colorectal cancer in IBD?
Colonoscopy 10 years post diagnosis then at intervals
What screening is done for colorectal cancer in those with a FH?
Colonoscopy at 50/55 years then at intervals
What screening is done for colorectal cancer in someone with a PMH?
Colonoscopy every 5 years