Hepatitis Flashcards

1
Q

Acquired from: Picornaviridae
MOT: Fecal Oral
Incubation: 28 days
Chronicity: No

A

Hepatitis A

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2
Q

Usually seen in the feces of patient with Hepa A during INCUBATION and EARLY ACUTE INFECTION

A

HAV Antigen

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3
Q

Primary Marker for Hepatitis A infection

A

IgM anti-HAV

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4
Q

Hepatitis A: Marker for immunity; persist for life

A

IgG anti-HAV

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5
Q

Detection of Hepatitis A in clinical, food, and water

A

HAV RNA

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6
Q

Family: Hepadnaviridae
MOT: Parenteral, Sexual, Perinatal
Incubation: 30-180 days
Chronicity: Yes

A

Hepatitis B

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7
Q

Hepatitis B marker for:

  • Active Infection
  • First Marker to appear
  • Important Marker for Screening Blood donors
A

HBsAg (surface)

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8
Q

Hepatitis B marker for:

  • High degree of INFECTIVITY & high vertical transmission risk
  • Active Replication
A

HBeAg (envelope)

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9
Q

Hepatitis B marker for:

  • cannot be detected in serum due to the envelope that masks it
  • retrieved by Biopsy only in the liver
A

HBcAg (core)

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10
Q

Hepatitis B Marker:

  • Current or Recent Infection
  • Useful in detecting Window period
A

IgM Anti-Hbc

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11
Q

Hepatitis B Marker:

  • life-long marker
A

IgG Anti-Hbc

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12
Q

Hepatitis B Marker:

  • Recovery from infection
  • Convalescence marker (good prognosis)
A

Anti-Hbe

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13
Q

Hepatitis B Marker:

Immunity to hepatitis B (Protective titer: > 10 mIU/mL)

A

Anti-Hbs

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14
Q

Acute, Atypical, or occult Hepatitis B

A

HBV DNA

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15
Q

Hepatitis B marker:

Used to monitor for effectiveness of therapy

A

Viral Load Test

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16
Q

Highly correlated with the presence of whole virus replication and potential infectivity of patient

A

HBV DNA

17
Q

Hepatitis C is acquired from the family of

A

Flaviviridae

18
Q

Family: Hepadnaviridae
MOT: Parenteral, Sexual, Perinatal
Incubation: 7-8 weeks
Chronicity: Yes

A

Hepatitis C
(Non-A Non-B Hepatitis)

19
Q

Hepatitis C Marker:

Current or past infection

A

Anti-HCV

20
Q

Hepatitis C Marker:

Viral Load Test to monitor effectiveness of therapy

A

HCV RNA

21
Q

aka Post Transfusion Hepatitis

A

Hepatitis C

22
Q

Surrogate test for HCV

A

Increase ALT
(+) Anti-Hbc

23
Q

Specific Test for HCV

A

(+) Anti-HCV

24
Q

Treatment for Hepatitis C and Kaposi Sarcoma

A

IFN alpha

25
Q

Acquired from the family of DELTA viruses (RNA)

A

Hepatitis D

26
Q

Family: Delta virus
MOT: Mostly Parenteral but can be transmitted Sexual, Perinatal
Chronicity: Yes

A

Hepatitis D

27
Q

Hepatitis D:

Coninfection

A

SiMultaneously
IgM

28
Q

Hepatitis D:

Superinfection

A

Seqqqqquentialy
IgG

29
Q

Hepatitis E is acquired from the family of

A

Hepeviridae
Caliciviridae

30
Q

Family: Hepevirus / Calicivirus
MOT: Fecal Oral
Incubation: 2-6 weeks
Chronicity: No

A

Hepatitis E

31
Q

Hepatitis E Marker:

Current Infection

A

IgM anti-HEV

32
Q

Hepatitis E Marker:

Current/Past Infection

A

IgG anti-HEV

33
Q

Hepatitis E Marker:

HEV RNA

A

Current infection

34
Q

associated with fulminant liver failure in pregnant woman

A

Hepatitis E

35
Q

ORDER OF APPEARANCE OF HEPA B MARKERS

S E C E S
Antigen Antibody

A

SE CES

36
Q

May be transmitted by clotting factor components

A

Hepatitis A
Infectious Hepatitis

37
Q

Dane particle is found in hepatitis

A

Hepatitis B
Serum Hepatitis