Henoch-Schonlein Purpura Flashcards
1
Q
What sort of vasculitis is Henoch-Schonlein Purpura?
A
It is a IgA mediated small vessel vasculitis
2
Q
What other condition does it overlap with?
A
IgA Nephropathy
Berger’s disease
3
Q
What do you need to make the diagnosis?
What is the classic triad of HSP?
A
Palpable purpuric rash+ (atleast one of the following):
Haematuria +/- Arthralgia +/- Proteinuria
4
Q
What causes it?
A
Any infection but is thought it could mainly be Strep Throat.
5
Q
What investigations should be done?
A
- BP and urine dip
- Isolated haematuria doesn’t require investigation.
- If High BP, Significant Proteinuria, or reduce UO - then do blood tests:
- U&Es, LFTs, Albumin, ASOT and anti-DNAase B.
6
Q
What is the management?
A
- Analgesia
- Follow up BP and Urinalysis for all - frequency depends on proteinuria or not.
7
Q
When would you admit them?
A
Admit if nephrotic/nephritic syndrome, severe joint pain or abdominal pain.
8
Q
What % of children will have renal involvement?
A
50% will have renal involvement but <1% will progress to ESRF.
9
Q
What risk factors make renal involvement more likely?
A
- Age > 4 years
- Persistent purpura >1/12
- Severe abdominal pain
