Cow's Milk Protein Intolerance/Allergy Flashcards
1
Q
What % of all children have CMPI/CMPA?
A
3-6%
2
Q
When does it typically present?
A
In the first 3 months of life of formula fed babies
3
Q
What are the 2 types of allergic reaction?
A
IgE mediated
Non-IgE mediated
4
Q
How do the terms CMPA and CMPI differ?
A
CMPA stands for immediate reactions
CMPI for mild-moderate dalyed reactions.
5
Q
What are some features of CMPA/CMPI?
A
- Regurgitation and vomiting
- Diarrhoea
- Urticaria, atopic eczema
- ‘Colic’ symptoms: irritability, crying
- Wheeze, chronic cough
- Rarely angioedema and anaphylaxis may occur
6
Q
How is the diagnosis made and what are some investigations you can do for it?
A
The diagnosis is ually made clinically.
Some investigations you could do are:
- Skin prick/patch test
- Total IgE and specific IgE (RAST) for cow’s milk protein.
7
Q
What % are also intolerant to soya milk?
A
10%
8
Q
How should CMPI/CMPA be managed in formula-fed babies?
A
- First line - extensive hydrolysed formula (eHF)
- Second line or if severe- Amino-acid-based formula (AAF)
9
Q
How should CMPA/CMPI be managed in breast fed babies?
A
- Continue breastfeeding
- Eliminate cow’s milk protein from mother’s diet
- Use eHF milk when breastfeeding stops (until 12 months of age and at least for 6 months.)
10
Q
When does CMPI usually resolve?
A
1-2 years of age
