Congenital Infections Flashcards
1
Q
What are the major congenital infections that are encountered? (Think TORCH)
A
- Toxoplasmosis
- Other (syphilis, Parvovirus B19, VZV, HIV)
- Rubella
- Cytomegalovirus
- Herpes simplex virus.
2
Q
What are some characteristic features of rubella infection?
A
- Sensorineural deafness
- Congenital cataracts
- Congenital heart disease (e.g. patent ductus arteriosus)
- Glaucoma
3
Q
What are some characteristics features of toxoplasmosis?
A
- Cerebral calcification
- Chorioretinitis
- Hydrocephalus
4
Q
What are some characteristic features of cytomegalovirus?
A
- Growth retardation
- Purpuric skin lesions
5
Q
What infection has the highest chance of fetal damage if caughter early in the pregnancy?
A
Rubella
Maternal rubella in the first 8-10 weeks of pregnancy can cause fetal damage in up to 90% of infants and multiple defects are common.
6
Q
After how many weeks is fetal damage rare as a result of maternal rubella infection?
A
16 weeks
