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Pharmacology > Hema Drugs > Flashcards

Hema Drugs Flashcards

1
Q

Treatment for iron toxicity ? (3)

A
  1. Deferoxamine IV
  2. Deferasirox
  3. Deferiprone (oral)
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2
Q

Types of Growth Factor :
Epoetin alfa

A

Erythroid

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3
Q

Types of Growth Factor :
Filgrastim

A

Myeloid

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4
Q

Types of Growth Factor :
Oprelvekin

A

Megakaryocyte

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5
Q

Samter Triad

A
  1. Sensitivity to aspirin
  2. Asthma
  3. Nasal polyp

“ SAAN si SAM? “

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6
Q

MOA of Abciximab

A

Inhibits glycoprotein IIb / IIIa receptors found on the surface of platelets.

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7
Q

GPIIb / IIIa inhibitors used as anti-platelets?

A
  1. Abciximab
  2. Eptifibatide
  3. Tirofiban

“ May 2-3 pack ABs ang mga taga FIBA “

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8
Q

ADP inhibitors used as anti-platelets

A
  1. Clopidogel
  2. Ticlopidine
  3. Prasugrel
  4. Ticagrelor

“ A DiP in TiTi Pool with Cupid”

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9
Q

Moa of cilostazol?

A

PDEIII Inhibitor

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10
Q

Antidote for heparin toxicity?

A

Protamine

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11
Q

Clotting factors affected by Warfarin ?

A

Vitamin K - dependent clotting factors ( IX, X, VII, II)

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12
Q

Antidote for Warfarin toxicity?

A
  1. Vitamik K (slow)
  2. FFP (fast)
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13
Q

Parameter monitored when taking Heparin?

A

aPTT

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14
Q

Parameter monitored when taking Warfarin?

A

PT

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15
Q

Monoclonal antibody used for reversal of Dabigatran toxicity?

A

Idarucizumab

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16
Q

Antidotes to fibrinolytics ?

A

Aminocaproic acid / Tranexamic acid

17
Q

Use, Mechanism, Side effect of Tranexamic acid?

A
  1. tPA Inhibitor
  2. Prevents acute bleeding episodes
  3. May cause thrombosis
18
Q

Act by inhibiting GP IIb / IIIa .

A
  1. Abciximab
  2. Tirofiban
  3. Eptifibatide
19
Q

Major contraindication for thrombolytic agent alteplase.?

A

Hemorrhagic stroke

20
Q

Moa Rituximab

A

Decreases level of B-cells in inflammation

21
Q

Drugs that block binding of ADP to P2Y12 ? (3)

A

Clopidogrel
Ticlopidine
Prasugrel

22
Q

Drugs that block GP IIIa / GP IIb? (3)

A

Abciximab
Tirofiban
Eptifibatide

GP 2-3 Abs Fiba players

23
Q

Drugs that inhibit PDE3 ? (2)

A

Cilostazol
Dipyridamol

24
Q

Low molecular weight heparin ? (3)

A

Low FED
Fraxiparine
Enoxaparin
Dalteparin

25
Q

Direct blockers of Clotting factor IIa ?

A

Dabigatran
Argatoban
Desirudin
Bivalirudin

Dabig Argument of Desiree & Bival

26
Q

Direct inhibitor of Clotting Factor Xa?

A

Fondaparinux- parenteral
Apixaban - oral
Rivaroxaban - oral
Edoxaban- oral

Stuart FARE

Pharmacology (12 decks)

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