Heart Failure Flashcards
In heart failure more common in men or women?
Men
How does heart failure incidence change as you age?
Between the ages and 40 and 80, incidence doubles with each decade
2 widely accepted definitions of heart failure
1) A cardiac disorder that prohibits delivery of sufficient output to meet perfusion requirements of metabolising tissues
2) A clinical syndrome caused by abnormality o the heart and recognised by characteristic pattern of haemodynamic and hormonal responses
4 main causes of heart failure
- Coronary artery diseases
- Hypertension
- Cardiomyopathy
- Valvular heart disease
4 aggravating factors of heart failure
- Cardiac arrhythmias
- Hypertension
- Anaemia
- Infections
What main 3 physiological changes cause the majority of signs and symptoms in heart failure?
Reduced cardiac output (peripheral hypoperfusion)
Fluid retention (congestions)
Increased sympathetic activity
What symptoms and signs result from reduced cardiac output
Symptoms= fatigue Signs= cool skin, peripheral cyanosis
What signs and symptoms result from fluid retention
Symptoms= dyspnoea, oedema Signs= Basal crackles, raised JVP, ankle swelling, ascites
What are ascites
abnormal fluid collection in perineal cavity
Distended stomach
What signs result from increased sympathetic activity
Tachycardia
Sweating
How might the pulse appear in somebody with heart failure
Alternating pulse
Name 6 complications that can result from heart failure
Intravascular thrombosis Infection Functional valvular dysfunction Multi organ failure Cardiac arrhythmias Sudden death
What examples of intravascular thrombosis can result from heart failure
Pulmonary embolism
Systemic embolism
What infections most commonly result from heart failure
Chest infection
Ulcerated cellulitic legs
What functional valvular dynsfunctions can occur from heart failure?
Mitral regurgitation
Tricuspid regurgitation
Which organs are most likely to fail as a result of heart failure
Renal failure
Liver failure
What cardiac arrhythmias are most commonly detected in heart failure?
Atrial fibrillation
Ventricular fibrillation
Ventricular tachycardia
How may an ECG of somebody with heart failure appear
- Inferior Q waves
- Anterior T waves and ectopics
- Left bundle branch block
What may a chest x-ray of somebody with heart failure show?
- Pulmonary congestion
- Pulmonary oedema
Where in BNP secreted from? In response to what?
Secreted by myocardial cells in response to raised left atrial pressure
4 changes that occur when BNP levels increase
- Promotes natriuresis
- Promotes vasodilation
- Inhibits ADH release
- Inhibits aldosterone release
What is natriuresis
Excretion of sodium in urine
How can BNP levels be used to diagnose heart disease
Levels of >100pg/ml
Describe diagnostic pathway for heart failure if patient has had previous MI
Specialist assesment and doppler echo
Abnormal echo= systolic or diastolic dysfunction
Normal echo= heart failure unlikely
Describe diagnostic pathway for heart failure if patient has no previous MI
Measure BNP levels in blood
If >100pg/ml then do an echo
If abnormal, systolic or diastolic dysfunction
If BNP/ echo is normal, heart failure in unlikely
What is the most common kind of heart failure?
Systolic heart failure
Define systolic heart failure
Inability of heart to contract efficiently to eject adequate volumes of blood to meet bodys metabolic demand
Define diastolic heart failure
Reduction in heart compliance resulting in compromised ventricular filling and less ejection
Define left sided heart failure
Inability of the left ventricle to pump adequate amount of blood–> pulmonary circulation congestions and pulmonary oedema.
Why does left side heart failure often lead to right side heart failure
Due to pulmonary hypertension
Define right sided heart failure
Inability to right ventricle to pump blood leading to systemic venous congestion therefore peripheral oedema and hepatic congestion and tenderness
What is congestive heart failure
Failure of both left and right ventricles
How should a combination of systolic and diastolic heart failure be treated?
- Treat aetilogical and aggravating factors
- Treat fluid retention with diuretics
How should systolic heart failure be treated?
- Ace and BB for all grades of heart failure
- ARBs if ACE is not dolerated
- Spironolactone (for grade 3 and 4 only)
- Cardiac resynchronisation therapy
- Angiontensin receptor neprilysin inhibitor
What is spironolactone
Diuretic
When is a heart transplant advised for heart failure?
Congestive heart failure without any major organ failure, any major co-morbitity, any psychological disability or any severe pulmonary hypertension
What procedure is used in heart transplant for heart failure
Orthotopic transplant (fully replaced with donor heart)
Prognosis for heart transplant patients/
80% survive a year
Another way of saying diastolic heart failure?
Heart failure with normal ejection fraction (HeFNEF)
Why is there impaired left ventricular filling in diastolic heart failure?
Increased chamber stiffness/ decreased relaxation
What % of heart failures are HeFNEF?
50% of adult heart failure
How are HeFNEFs treated?
- Treat the underlyign cause
- Treat systolic components
- Treat fluid retention
- RAAS inhibition
- Beta blocker
What is acute heart failure?
Acute onset of symptoms due to acute event (mi, ruptured valve, ventricular aneurysm)
What immediate pharmacological treatments can be offered to a patient in acute heart failure
Iv diuretic
Oxygen
What immediate non pharmacoligcal treatments can be offered to a patient in acute heart failure
Ventilation
Ultrafiltration is diuretic resistant
What treatment should be offered to a patient in acute heart failure after theyve been stabilised
- ACE inhibitor/ ARB
- BB
- Aldosterone inhibitor
- Monitor renal function, electrolytes, BP and HR
What can cause acute heart failure?
- Acute MI
- Cardiac tachyarrhythmia
- Valvular heart disease
- Acute on chronic heart failure (can be triggered by infection, failure of take drugs)
What 4 things occur in acute heart failure that can explain signs and symptoms
- Pulmonary oedema
- Desaturation
- Reduced CO
- Sympathetic activation
How does pulmonary oedema present in acute heart failure
Severe dyspnoea
How does desaturation present in acute heart failure
Central cyanosis
How does reduced cardiac output present in acute heart failure
Cool skin, peripheral cyanosis
How does sympathetic activation present in acute heart failure
Tachycardia, sweating
What heart sound is present in heart failure
S3