HDV Flashcards

1
Q

Genoma

A

Smallest RNA genoma

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2
Q

Infection

Non esistono portatori cronici di solo HDV, è necessaria la presenza di HBV

A

Infection occurs only in the presence of HBV infection and is detected by demostrating anti-HDV (non è utile se IgM o IgG)

  1. COINFEZIONE: anti-HDV plus IgM anti-HBc
    - 5% of cases of acute coinfection results in chronic infection
  2. SUPERINFEZIONE: anti-HDV plus IgG anti HBc (core)
    - in almost all cases, HDV superinfection result in chronic infection. Si risolve raramente se non si risolve prima HBV infection
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3
Q

Prognosi

A

Nei soggetti con superinfection, il decorso verso la cirrosi è più rapido rispetto alla sola infezine cronica con HBV.

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4
Q

Tretment

A

Interferon alpha

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