Handout 3 Flashcards
the number of cells needed to kill half of the animals in a test group?
LD50
hylaruonidase, collagenase and fibrinolyse help with what virulence factor?
invasion
part of bacteria- the LPS in gram negative bacteria
endotoxins
exotoxins are secretes- like AB toxins etc.
toxin that affects the intestinal mucosa?
enterotoxin
what is a PAI? pathogenicity island?
this is when virulence factors are grouped together- often on a plasmid
increase their ability to cause disease obviously
what do the bacteria of a biofilm have?
quorum sensing- colony of bacteria with a biofilm.
we see this in the mouth
work against infection by destroying or inhibiting microorganisms on skin or mucus membranes
antiseptics
kill most, not all microbes – NOT given to patients except alcohol on skin
disinfectants
used to kill all microbial forms, even spores
sterilants
what is soap an example of?
antiseptic. uses detergent to remove oils
what is chlorohexidene example of?
antiseptic agent.
disrupts the bacterial cell membrane. residual activity
what does fluoride inhibit?
enolase. this is an enzyme that is found in organisms that use fermentation
hydrogen peroxide is a _____ agent
oxidizing
how does listerine work?
phenolic compounds disruptiong enzymes/denatures proteins
removes all life forms including spores – indicator organism is a spore forming bacteria – Bacillus or Clostridium
sterilization
