Handout 10 Flashcards

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1
Q

surrounds the genome of a virus?

A

capsid! capsule for bacteria

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2
Q

cellular or acellular?

A

acellular= no cytoplasm and no organelles.

no metabolic- steal that from the host

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3
Q

extracellular form of a virus?

A

virion

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4
Q

nucleocapsid contents

A

DNA or RNA
structural protein
enzymes and nucleic acid binding proteins
nucleocapsid may be the outer structure if naked

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5
Q

what’s the outer structure if the virus is nakie?

A

nucleocapsid

covered with plasma and spikes otherwise.

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6
Q

what viral proteins project out of the membrane for attachment?

A

VAPS, peplormers and spikes

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7
Q

what is the nucleocapsid structure?

A

it has capsomers.
helical or icosahedral forms
bacteriphages have additional structures attached to their head

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8
Q

what VAP does influence have?

A

HA = hemaggluttinin

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9
Q

are naked or enveloped more resistant to acids?

A

naked! envelope has a plasma- lipid- membrne so it needs moisture . acids are more resistant to drying and spread more easily.

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10
Q

where do DNA viruses replicate vs. RNA viruses?

A

DNA in the NUCELUS and RNA in the cytoplasm. (except for AIDS?)

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11
Q

what does TROPISM mean?

A

host cell type specificity. “looking for their trophy host”

example of Hep C is hepatotrophic

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12
Q

early phase vs. late phase

A
early= enzymes. PROTEINS needed for REPLICATION! enzymes
late= capsid strcutres
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13
Q

why is it hard for RNA to make eukaryotic ribosomes?

A

viruses have POLY (they’re sluts)
and the eukaryotes have MONO
so they will make mono mRNA
host splicing to cleave the viral mRNA

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