haemolytic uraemic syndrome Flashcards
1
Q
what is haemolytic uraemic syndrome
A
thrombosis in small blood vessels throughout the body, usually triggered by shiga toxins from either e.coli O157 or shigella
2
Q
classic triad in HUS
A
microangiopathic haemolytic anaemia
AKI
thrombocytopenia (low platelets)
3
Q
presentation of HUS
A
around a week after onset of diarrhoea
Fever
Abdominal pain
Lethargy
Pallor
Reduced urine output (oliguria)
Haematuria
Hypertension
*Bruising
*Jaundice (due to haemolysis)
Confusion
4
Q
management of HUS
A
stool culture to determine causative organism
hospital admission
IV fluids
treat hypertension
blood transfusion
haemodialysis
