diseases Flashcards
type 1 renal tubular acidosis cause
is due to pathology in distal tubule
- unable to excrete hydrogen ions
presentation of type 1 renal tubular acidosis
failure to thrive in children
hyperventilation to compensate for metabolic acidosis
chronic kidney disease
bone disease (osteomalacia)
treatment of type 1 renal tubular acidosis
bicarbonate
Type 2 Renal Tubular Acidosis cause
due to pathology in the proximal tubule. The proximal tubule is unable to reabsorb bicarbonate from the urine into the blood. Excessive bicarbonate is excreted in the urine
electrolyte presentation of type 2 renal tubular acidosis
oral bicarbonate
Type 4 Renal Tubular Acidosis cause
caused by reduced aldosterone
due to adrenal insufficiency, medications such as ACEi and spironolactone, SLE, diabetess, HIV
results of type 4 renal tubular acidosis
Hyperkalaemia
High chloride
Metabolic acidosis
Low urinary pH
management of type 4 renal tubular acidosis
fludrocortisone. Sodium bicarbonate and treatment of the hyperkalaemia may also be required
seminoma
germ cell tumour of the testicle
presentation of seminoma
painless testicular lump
man 40-50years
normal AFP and HCG
which prostatic zone enlarges with benign prostatic hyperplasia
transitional zone