Haematuria Flashcards
What is haematuria?
Blood in the urine
What is visible and non-visible haematuria called respectively?
Visible - macroscopic/gross
Non visible - microscopic/dipstick positive
When is haematuria diagnosed?
Presence of at least 5 red blood cells per high powered field in 3 consecutive centrifuge specimens obtained at least 1 week apart
OR
Dipstick (usually dipstick tbh)
What is spurious contamination?
Discoloured urine caused by contaminants (blood, etc) from a non-urinary tract source
List some lower urinary tract symptoms that may present in conjunction with haematuria
Hesitancy
Frequency
Urgency
Dysuria
List some upper urinary tract symptoms that may present in conjunction with haematuria
Renal colic (loin to groin pain)
List causes of red appearing spurious contamination?
Menstruation Food (rhubarb, beetroot) Myoglobin in urine Drugs Toxin (lead, mercury)
How much blood does it take to give the urine a red appearance?
1ml
When is myoglobin found in the urine?
Bywater’s syndrome (crush syndrome)
Rhabdomyolisis (statins)
McArdle sydrome
I.e damage to muscles
Which drugs can cause spurious contamination?
Nitrofurantoin (UTI treatment)
Rifampicin
Chloroquine
Senna containing laxatives
List the appearance of brown appearing spurious contamination
Porphyrias
Urobilinogen in urine
When is urobilinogen found in urine?
Liver dysfunction
Icterus
Haemolysis
Blood thinners increase incidence of haematuria. T/F
True in overdose - warfarin, heparin & aspirin
Which percentage of patients with frank haematuria have cancer?
20-30%
What are the risk factors for serious pathology of the urinary tract?
Smoking Chemical/dye exposure Gross haematuria >40 y/o History of urologic disorder History of irritative voiding symptoms History of UTI (reassuring) Analgesia abuse
Cystitic can cause frank haematuria. T/F
True