Haematology Malignancy Genetics Flashcards by Zoe Doak | Brainscape

Q

t(9;22) - Philadelphia chromosome

A

Chronic Myeloid Leukaemia (CML)

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Q

BCR-ABL gene

A

Chronic Myeloid Leukaemia (CML)

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Q

t(15;17)

A

APML

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Q

PML and RAR-alpha genes
(PML-RARA)

A

APML

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Q

t(8;14)

A

Burkitts Lymphoma

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Q

MYC oncogene

A

Burkitts

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Q

t(11;14)

A

Mantle Cell Lymphoma

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Q

deregulation of the cyclin D1 (BCL-1) gene

A

Mantle Cell Lymphoma

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Q

t(14;18)
increased BCL-2 transcription

A

follicular lymphoma

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Q

A

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