Anti-Thrombin III deficiency Flashcards
1
Q
Inheritance pattern of anti-thrombin III deficiency
A
autosomal dominant.
2
Q
What clotting factors does anti-thrombin III inhibit?
A
thrombin
Factor X
Factor IX
3
Q
Describe the different types of disorder which come under the heading of anti-thrombin III deficiency
A
- deficiency of normal antithrombin III
- production of abnormal antithrombin III
4
Q
Features of antithrombin III deficiency
A
- recurrent venous thromboses
- arterial thromboses (uncommon)
5
Q
Management of anti-thrombin III deficiency
A
- lifelong warfarin if clot occurs
- heparin during pregnancy
- antithrombin III concentrates (during surgery/childbirth)
6
Q
A
