Haematology Flashcards

1
Q

4 components of blood

A

Plasma
Platelets
Red blood cells
White blood cells

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2
Q

How many litres of blood in the body?

A

4-5 litres

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3
Q

What percentage of blood is plasma?

A

55%

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4
Q

What is blood plasma made up of?

A

Water, gases, nutrients, vitamins, hormones, proteins, electrolytes , wastes

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5
Q

Haematopoiesis

A

The production of all types of blood cells including formation, development and differentiation

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6
Q

What shape are RBCs?

A

Concave

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7
Q

Where are RBCs produced?

A

Bone marrow

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8
Q

What break down old RBCs?

A

Macrophages

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9
Q

What break down haemaglobin

A

Hepatocytes

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10
Q

Where is bile secreted?

A

Into the small intestine

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11
Q

What secretes nutrients from blood?

A

Small intestine

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12
Q

Where is nutrients in small intestine moved to?

A

Bone marrow to produce new RBCs

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13
Q

What substance is formed by breakdown of haemaglobin?

A

Bilirubin

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14
Q

Where is bilirubin secreted?

A

Into bile

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15
Q

What is heme?

A

An iron containing compound which forms the non protein part of haemaglobin

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16
Q

Another term for red blood cell

A

Erythrocyte

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17
Q

Two groups of white blood cells?

A

Granulocytes

Agranulocytes

18
Q

What two white blood cells are agranulocytes?

A

Monocytes

Lymphocytes

19
Q

What type of white blood cells are granulocytes?

A

Neutrophils
Eosinophils
Basophils

20
Q

Function of white blood cells?

A

Protect body against infection disease and foreign invaders

21
Q

Function of platelets

A

Stop bleeding by clumping and clotting blood vessel injuries

22
Q

List three main proteins in blood

A

Albumins
Globulin
Fibrinogen

23
Q

Three types of globulins

A

Alpha globulins- transports lipids
Beta globulins- transports lipids
Gamma globulins - antibodies

24
Q

Main gases in blood

25
What are the three steps to haemostasis after blood vessel injury?
Blood vessel spasm Platelet plug formation Blood coagulation
26
What do platelets release in haemostasis?
Seratonin to constrict smooth muscle in blood vessel walls
27
How do platelets form a plug?
They stick to each other and to the broken vessel and are exposed to collagen. This helps control blood loss
28
What releases thrombin after tissue damage?
Prothrombin (activated by prothrombin activator)
29
What releases fibrin after tissue damage?
Fibrinogen (activated by thrombin)
30
Someone with type A blood has what antigens and what antibodies?
Anti B antibody | A antigens
31
Type B blood has what antibodies and what antigens?
Anti- A antibody | Antigen B
32
Type AB blood has what antibodies and what antigen?
No antibodies | A and B antigens
33
Type O blood has what antibodies and what antigen?
A and B antibodies | No antigens
34
Which blood group is the universal recipient?
AB as if contains no antibodies
35
What is the third antigen that RBCs can carry?
RHD antigen
36
If you have RHD antigen in you RBCs are you rhesus negative or rhesus positive?
Rhesus positive
37
What is the name of the antibody against RHD? (Sometimes Present in those without the RHD antigen on their RBCs)?
Anti- D antigen
38
What can happen if a fetus with RH positive blood’s blood enters its RH negative mothers blood stream during childbirth?
The mother produces anti- D antibodies against RH-positive blood cells between pregnancies. Therefore in the next pregnancy, maternal antibodies attack fetal red blood cells causing a miscarriage.
39
What is a thrombus?
A blood clot
40
What is an embolus
Anything that travels through a blood vessel until it reaches a vessel too small to let it pass, then restricts blood flow.