Haematology 6: Venous Thrombosis Flashcards
List 4 anticoagulant molecules expressed by the endothelium ?
TFPI
Thrombomodulin
EPCR
Heparans
When using unfractionated heparin, how could you measure the level to see if the treatment is in the therapeutic window ?
APTT
anti-Xa assay
Which DOAC inhibits factor IIa ?
Dabigatran
Which DOACs inhibit factor Xa ?
Rivaroxiban
Apixaban
Edoxaban
(They have an X in the name)
What reading is INR derived from ?
PT
Can Warfarin be given during pregnancy ?
No its teratogenic
Which factors are inhibited by Warfarin ?
10
9
7
2
Protein C and Protein S
Remember 1972
List 5 risk factors for thrombosis ?
Cancer Surgery Obesity Elderly Immobility
Which of these factors are associated with a higher risk of recurrence of DVT ?
Male sex Female Sex Proximal thrombosis Distal thrombosis Post surgery Idiopathic
Male sex
Proximal Thrombosis
Idiopathic