Haematology 6: Venous Thrombosis Flashcards

1
Q

List 4 anticoagulant molecules expressed by the endothelium ?

A

TFPI
Thrombomodulin
EPCR
Heparans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

When using unfractionated heparin, how could you measure the level to see if the treatment is in the therapeutic window ?

A

APTT

anti-Xa assay

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which DOAC inhibits factor IIa ?

A

Dabigatran

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which DOACs inhibit factor Xa ?

A

Rivaroxiban
Apixaban
Edoxaban

(They have an X in the name)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What reading is INR derived from ?

A

PT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Can Warfarin be given during pregnancy ?

A

No its teratogenic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which factors are inhibited by Warfarin ?

A

10
9
7
2

Protein C and Protein S

Remember 1972

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

List 5 risk factors for thrombosis ?

A
Cancer
Surgery
Obesity
Elderly
Immobility
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which of these factors are associated with a higher risk of recurrence of DVT ?

Male sex
Female Sex
Proximal thrombosis
Distal thrombosis 
Post surgery 
Idiopathic
A

Male sex
Proximal Thrombosis
Idiopathic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly