H+N pt. 1 Flashcards
What portion of head and neck cancer patients present with early-stage disease?
1/3
2/3 of oral/pharynx present with locally advanced disease at what sites? What are the most common stages of these occurrences?
Primary Site and Cervical Node, Stage III and IV
What are the common site of metastasis for head and neck cancers? (5 answers)
Lung is the most common, Mediastinal Nodes, Liver, Brain, and Bone
In what specific cancers is distant metastasis a common occurrence? (2 answers)
Hypo and Nasopharynx
What is the path of spread for head and neck cancers? (1 answer)
Nerves
What is the treatment standard for H&N patients that have inoperable or unresectable tumors/ Stage III and IV?
Chemotherapy and Radiation Therapy
What is the definition of cancerization?
The prevalence of a second cancer resulting from treatment in the area of the original disease
What percentage of H&N Patients have a risk of developing second cancer after being cured of their first cancer?
Greater than 20%
What is the leading cause of death in patients with early H&N tumors?
Second Primary Tumor
What is the five-year survival rate of H&N Cancer?
60%
What age groups does oral cancer commonly affect?
55-64 YO
What age groups does laryngeal cancer commonly affect?
65-74 YO
What is the cause of the higher prevalence of nasopharynx cancer in Asian nations? (2 answers)
Diet with high salt and Tobacco use
What is the cause of the higher prevalence of Oral cancer in Indian nations? (1 answers)
Betel Nut Chewing
What are the etiologic factors of H&N Cancer? (3 answers)
Smoking, Alcohol, and Tobacco use
What can smokeless tobacco cause besides malignancy?
Pre-malignant lesions known as Leukoplakia, which are white patches
What are the environmental etiologic factors of H&N Cancer? (4 answers)
Outdoor occupations, Furniture working, fumes, formaldehyde
What are the radiation etiologic factors of H&N Cancer?
Exposure at a young age affecting the thyroid and salivary gland
What are the virus etiological factors of H&N Cancer? (3 answers)
Epstein Barr Virus (EBV), Herpes Simplex 1, HPV
What is the pattern of prognosis from the lips to hypopharynx?
decreases as you go backwards
In what situations is prognosis unfavorable for those having Head and Neck cancer? (4 answers)
Disease that: Cross the midline, exhibit endophytic growth, are poorly differentiated, present as Non-squamous Cell carcinomas
For advance H&N cases, what best describes their LN, tumor and invasion behavior? (3 answers)
Fixed Lymph Nodes, Fixed Lesion or Fixed cranial nerve involvement
What is special about the organ and structure included in the H&N region? (2 answers)
Serve dual purpose in the respiratory and digestive systems
What is the staging of H&N cancer based on? (1 answer)
involvement of adjacent structure
What is the circular region located between the nasal cavity, nasopharynx and oropharynx?
Waldeyers region
What is the significance of tumor development within the lower nasopharynx to the upper oropharynx region?
Tumors can interfere with the natural response of the soft palate to keep food from entering the nasal passage and also restrict air passages
Describe tonsils and their purpose.
Tonsils are a band of lymphoid tissue, they provide protection against airway infection and form a barrier between the aerodigestive tract
What is the vertebral level of the inferior margin of the nasopharynx?
C1
What is the vertebral level of the Oropharnyx?
C2-C3
What is the vertebral level of the Epiglottis?
C3
What is the vertebral level of the true vocal cord?
C4
What are some effects of salivary gland tumors? (3 answers)
facial paralysis, neuropathy, and interruption of blood supply