Anal Cancer Flashcards

1
Q

Anal cancer is slightly more common in women. True or False?

A

True

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2
Q

What is the median age of anal cancer pt?

A

60 yo

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3
Q

What is the age range for anal cancer?

A

30-60 yo

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4
Q

What is the 5 year survival rate for anal cancer?

A

68%

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5
Q

What is the contribution to an increase of prevalence in men under 45?

A

anal intercourse

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6
Q

What are some other etiological contributors to anal cancer?

A

Infection, HPV, and immunosuppression

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7
Q

How long is the anal canal?

A

3-4 cm

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8
Q

What are the checkpoints from most inferior to most superior?

A

Anal verge, Dentate Line, Pectate Line

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9
Q

What zone ranges is within the anal verge to Dentate line?

A

Squamous Zone (Strat Epi)

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10
Q

What zone ranges is within the Dentate line to Pectate line?

A

Transitional Zone

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11
Q

What zone ranges is within the Pectate line to rectum?

A

Colorectal Zone (Colum Epi)

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12
Q

What LN are involved above the dentate line?

A

internal iliacs and sacral nodes

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13
Q

What LN are involved below the dentate line?

A

inguinal nodes

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14
Q

What is the clinical presentation of anal cancer?

A

Bleeding is most common, pain, change in bowel habits, itching

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15
Q

What are some examinations that can be performed for anal cancer detection?

A

DAE (Digital Anorectal Exam), Palpation of inguinal nodes, Anoscopic, and proctoscopic exams, Biopsy

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16
Q

What is the pathology of Anal Cancer?

A

80% squamous cell carcinoma

17
Q

What staging system is used for Anal cancer?

A

TNM system

18
Q

What are the treatment options for anal cancer?

A

Chemoradiotherapy and AP Resection

19
Q

What is the preferred treatment technique for anal cancer per the NCCN?

A

IMRT (AP/PA or 4F), 60 Gy

20
Q

What are the boost treatment borders and limits for Anal cancer tx?

A

Ant fields over each inguinal and abut on PA lateral fields

21
Q

What are OAR for Anal Cancer tx?

A

Femoral heads, Genitalia, Small bowel, Bladder and Perineum

22
Q

What are common side effects of anal cancer RT?

A

N/V, Diarrhea, Erythema, Desquamation, Chemo presents more toxic side effects