Anal Cancer Flashcards
Anal cancer is slightly more common in women. True or False?
True
What is the median age of anal cancer pt?
60 yo
What is the age range for anal cancer?
30-60 yo
What is the 5 year survival rate for anal cancer?
68%
What is the contribution to an increase of prevalence in men under 45?
anal intercourse
What are some other etiological contributors to anal cancer?
Infection, HPV, and immunosuppression
How long is the anal canal?
3-4 cm
What are the checkpoints from most inferior to most superior?
Anal verge, Dentate Line, Pectate Line
What zone ranges is within the anal verge to Dentate line?
Squamous Zone (Strat Epi)
What zone ranges is within the Dentate line to Pectate line?
Transitional Zone
What zone ranges is within the Pectate line to rectum?
Colorectal Zone (Colum Epi)
What LN are involved above the dentate line?
internal iliacs and sacral nodes
What LN are involved below the dentate line?
inguinal nodes
What is the clinical presentation of anal cancer?
Bleeding is most common, pain, change in bowel habits, itching
What are some examinations that can be performed for anal cancer detection?
DAE (Digital Anorectal Exam), Palpation of inguinal nodes, Anoscopic, and proctoscopic exams, Biopsy
What is the pathology of Anal Cancer?
80% squamous cell carcinoma
What staging system is used for Anal cancer?
TNM system
What are the treatment options for anal cancer?
Chemoradiotherapy and AP Resection
What is the preferred treatment technique for anal cancer per the NCCN?
IMRT (AP/PA or 4F), 60 Gy
What are the boost treatment borders and limits for Anal cancer tx?
Ant fields over each inguinal and abut on PA lateral fields
What are OAR for Anal Cancer tx?
Femoral heads, Genitalia, Small bowel, Bladder and Perineum
What are common side effects of anal cancer RT?
N/V, Diarrhea, Erythema, Desquamation, Chemo presents more toxic side effects
