Gut-Health Connection Flashcards
What is the gut microbiome
Healthy gut helps break down macronutrients and aids in the absorption of essential nutrients; the gut houses significant portion of the body’s immune system
What is the role of the gut microbiome
Helps regulate immune responses, defend against harmful pathogens, create tolerance to the food we eat and our innate cells; also prevents the overgrowth of potentially harmful bacteria
What influences the integrity of the gut lining
A balanced gut microbiota
What is leaky gut
Increased intestinal permeability
What is gut dysbiosis
Increased leaky gut, chronic inflammation, autoimmune diseases and other chronic health conditions
What is gut microbiota
Microorganisms that reside in the digestive tract
What are nutrigenomics
Studies how nutrients interact with genes
Examples of differences in nutrient requirements
MTHFR gene variants, APOE, Vit D Receptor, SLC12A1/SLC23A2
What are MTHFR gene variants
Impacts the body’s ability to metabolize FOLATE and can increase risk of neural defects, cardiovascular disease, and mental health
What is APOE
May respond differently to dietary fats and antioxidants compared to those with other variants; can result in altered cholesterol levels, increased risk of cardiovascular, and Alzheimer’s disease
What is Vit D Receptor
VDR can affect how VIT D is utilized in the body, risks are osteoporosis, autoimmune diseases
What is SLC12A1/SLC23A2
Affects the absorption and utilization of Vit C, may influence immune function, skin health, and antioxidant activity
What is epigenetics
Changes in gene activity that do not involve DNA code changes; EX: Folate, Vit B12 can impact epigenetic changes which can be linked to health outcomes
