Digestive & Elimination Health Flashcards

1
Q

What are they key functions of the digestive system

A

The digestive system breaks down food through mechanical and chemical processes, absorbs vital nutrients required for metabolic balance, eliminates waste to maintain bodily functions

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2
Q

The digestive system is responsible for breaking down food into nutrients that the body uses for:

A

Growth, energy production, and tissue repair

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3
Q

What are the 3 key processes of the digestive system

A

Digestion = mechanical & chemical breakdown of food; Absorption = uptake of essential nutrients into the body; Elimination = removal of waste products

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4
Q

Salivary gland breakdown

A

Parotid, submandibular, sublingual

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5
Q

Throat breakdown

A

Pharynx, vocal chords, esophagus

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6
Q

Small intestine breakdown

A

Duodenum, jejunun, lleum

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7
Q

Mouth breakdown

A

Palate, uvula, teeth, tongue

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8
Q

Large intestine breakdown

A

Transverse colon, ascending colon, cecum, descending colon, sigmoid colon, rectum

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9
Q

What is chemical digestion

A

When enzymes and gastric acids chemically degrade macromolecules into simpler components; key breakdown products are monosaccharides, amino acids, fatty acids

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10
Q

What is absorption

A

After digestion, nutrients are absorbed primarily in the small intestine, with some absorption also occurring in the large intestine

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11
Q

What do the small intestines absorb

A

Up to 90% of nutrients including glucose, amino acids, fatty acids, vitamins, water

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12
Q

What do the large intestines absorb

A

Fewer nutrients than the small intestines, mostly water, electrolytes, and some nutrients from waste materials

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13
Q

What is elimination

A

After nutrient extraction, the leftover waste material moves into the large intestine for water reabsorption and eventual expulsion as feces

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14
Q

What is effective elimination critical for

A

Preventing toxic buildup and maintaining the balance of gut microbiota

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15
Q

Role of the large intestine

A

Maintain electrolyte balance, houses beneficial bacteria that further break down residual nutrients, produces essential metabolites, such as short-chain fatty acids (SCFAs)

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16
Q

What is the impact of dysfunction such as inadequate chewing or reduced saliva production

A

Can lead to incomplete breakdown of macronutrients, impairs subsequent digestion and nutrient absorption, could lead to digestive discomfort, malabsorption, or nutrient deficiencies

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17
Q

Roll of the esophagus and digestion

A

Food travels down the esophagus after being swallowed, peristalsis propels food into the stomach, the lower esophageal sphincter (LES) prevents food from moving back up the stomach; if LES down not properly close, it can lead to acid reflux and GERD

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18
Q

What is the small intestine

A

The small intestine is the primary site for nutrient breakdown and absorption and is divided into 3 sections: the duodenum, jejunum, and ileum

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19
Q

Dysfunction in the small intestine

A

Causes: impaired enzyme production, inflammation, small intestinal bacterial overgrowth (SIBO), damage to villi; Consequences: digestive disorders, malnutrition and nutrient deficiencies, symptoms like constipation, bloating, etc.

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20
Q

What does the liver do in relation to the digestive system

A

The liver produces bile, which emulsifies fats, making them easier to digest and it detoxifies harmful substances and processes absorbed nutrients before they enter general circulation

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21
Q

What does the gallbladder do in relation to the digestive system

A

The gallbladder stores bile until its needed for fat digestion and releases bile into the small intestine to aid in the digestion of dietary fats

22
Q

Dysfunctions in the liver and gallbladder

A

Causes: inadequate bile production, impaired bile flow, cholecystectomy (experience significant digestive symptoms and need careful care); Consequences: fat digestion is impaired and bile flows directly into small intestines (in cases of gallbladder removal)

23
Q

What does the large intestine do in relation to the digestive system

A

Absorbs water and electrolytes, such as sodium and potassium, compacts waste into feces, stores feces in the rectum until elimination, houses the intestinal microbiota

24
Q

What does the rectum and anus do in relation to the digestive system

A

The rectum stores fecal matter and the anus (sphincters = ring-like muscles) control the release of feces

25
What are the key bacterial groups in a healthy microbiome
Bacteroidetes, firmicutes, actinobacteria, proteobacteria
26
What are drivers of low diversity dysbiosis
Genetic factors, antibiotic use, hepatic inflammation (liver), chronic stress, poor diet, environmental toxicants, lack of exposure to microbes
27
What is low diversity dysbiosis
Low diversity dysbiosis refers to a decrease in the variety of microbial species in the gut, which is crucial for maintaining health
28
What are health implications of low diversity
Gut-related disorders (IBS, IBD, SIBO), metabolic disorders like obesity and type 2 diabetes, immune dysregulation and autoimmunity, mental health and gut-brain axis, increased susceptibility to infections
29
What is pathogenic overgrowth dysbiosis
An imbalance where harmful or pathogenic bacteria proliferate beyond their normal range which disrupts the healthy balance of the microbiome - commonly seen in conditions like SIBO, candida, H. pylori, C. diff
30
What is SIBO
SIBO is small intestinal bacteria overgrowth - when bacteria that normally resides in the large intestine overgrow in the small intestine. This interferes with digestion and nutrient absorption. This condition is associated with bloating, diarrhea, gas, and nutrient deficiencies. SIBO can lead to malnutrition, leaky gut, and systemic inflammation
31
What is Candida Overgrowth
Candida is a type of yeast and can overgrow and disrupt the balance of the gut microbiome. Systems are bloating, fatigue, sugar cravings, brain fog, and skin rashes. Chronic Candida overgrowth can trigger immune responses that lead to food sensitivities and autoimmune conditions
32
What is Clostridium difficile (C. diff) Infection
C. diff is a bacterium that can cause severe diarrhea, colitis, and inflammation of the colon. Overgrowth often occurs after antibiotic use when the balance of beneficial bacteria is disrupted. This can lead to severe dehydration and sepsis.
33
What is metabolic and weight issues
Overgrowth of harmful bacteria in the intestines can contribute to metabolic dysregulation which can lead to weight gain, insulin resistance, and obesity and type 2 diabetes.
34
What is intestinal inflammation and immune dysregulation
Overgrowth of pathogenic bacteria can trigger chronic low-grade inflammation in the gut, which can spread and contribute to autoimmune diseases, allergies, and chronic inflammation.
35
Drivers of loss of beneficial bacteria
C-section and lack of breastfeeding, lack of physical activity, aging and immuosenescence, sleep deprivation and circadian rhythm disruption
36
What are the 3 common probiotic strains
Lactobacillus acidophilus, bifidobacterium longum, saccharomyces boulardii
37
Benefit of probiotic lactobacillus acidophilus
Supports digestion, immune modulation, inhibits growth of pathogenic microbes, and relieves symptoms of IBS
38
Benefit of probiotic bifidobacterium longum
Promotes anti-inflammatory effects, synthesizes B vitamins, and improves barrier function
39
Benefit of probiotic saccharomyces boulardii
Effective in managing diarrhea and maintaining intestinal health, especially following antibiotic use
40
Benefit of prebiotic fructooligosaccharides (FOS)
FOS are short chains of fructose molecules naturally found in foods like onions, garlic, asparagus, and bananas. Highly fermentable by commensal bacteria including Bifidobacterium. They are resistant to digestion in the upper GI tract which allows them to be fermented by beneficial bacteria in the large intestines
41
Benefit of prebiotic Inulin
Inulin is a longer-chain form of fructose polymer found primarily in foods like chicory root, Jerusalem artichokes, and leeks. This prebiotic serves as a substrate for fermentation in the large intestines and promotes the excretion of butyrate.
42
Benefit of prebiotic Galactooligosaccharides (GOS)
GOS is another longer-chain polymer that is formed by Beta-galactosidase transgalactosylation. It feeds beneficial bacteria in the microbiome and helps regulate it. Can help prevent diarrhea or intestinal obstruction, regulate the intestinal floral, promote the growth of Bifidobacteria, help prevent cancers, improve lipid metabolism, improve mineral absorption, and modulate the immune system
43
Benefit of prebiotic Resistant Starch
Resistant starch is a form of starch that resists digestion in the small intestine and reaches the colon intact, where gut bacteria ferment it. It is found in foods like green bananas, cooked and cooled potatoes, and certain grains like oats and barley. They support the production of butyrate, improve insulin sensitivity, reduce the risk of colon cancer, improve digestive health
44
Benefit of prebiotic Pectins
Pectins are a type of soluble fiber found in high concentrations in fruits like apples, oranges, and berries. They are also found in higher concentrations in gently cooked fruits. Pectins are partially digested by commensal microbes, reduce inflammation, support intestinal motility, lower cholesterol levels by binding to bile acids, and improve constipation and diarrhea
45
What are key markers of the OAT (Organic Acids Test - urine)
Fungal markers, bacterial markers, nutrient deficiencies, energy production and mitochondrial function, detoxification
46
What is the SIBO breath test
A non-invasive diagnostic tool used to assess the presence of bacterial overgrowth in the small intestine Hydrogen gas production, methane gas production, combined hydrogen & methane
47
What is Zonulin testing
Zonulin is a functional marker used to assess increased intestinal permeability. It is a protein that regulates the tight junctions between intestinal epithelial cells. Elevated levels can indicate increased intestinal permeability which may indicate gastrointestinal and system health issues
48
What does a stool test tell us in functional medicine
High steatocrit indicates too much fat in the stool. This is a sign that the digestive system is not breaking down and absorbing fat adequately. Low levels of elastase-1 indicate exocrine pancreatic insufficiency. This occurs when the pancreas does not produce enough digestive enzymes which leads to poor breakdown and absorption of nutrients.
49
What are key nutrients for digestion and gut health
Glutamine, zinc, omega-3 fatty acids, vit D, magnesium, aloe vera, collagen, B vitamins, vit C, digestive enzymes, betaine HCI
50
What are the 2 types of fiber and what are their benefits
Soluble and insoluble fiber which help with bowel regulation, nutrient absorption, and gut homeostasis
51
What is soluble fiber
Soluble fiber dissolves in water and forms a gel-like consistency during digestion., Examples include plant pectin, beta-glucans, and gums. Sources are oats, flaxseeds, chia seeds, apples, carrots, psyllium husk, legumes, brussel sprouts, sweet potatoes. They slow digestion for better nutrient absorption and blood sugar regulation. Also improves diarrhea
52
What is insoluble fiber
Insoluble fiber does not dissolve in water well. It comes from the outer skins of plants and includes cellulose, hemicellulose, and lignin. It comes from whole grains, brown rice, quinoa, cruciferous veggies like broccoli & cauliflower, nuts, seeds, outer skins of fruits. Increases stool mass (preventing constipation), moves food along the digestive tract, and promotes detoxification.