Gram -ve rods - part 2 Flashcards

1
Q

Describe Shigella species in terms of their movement and where they are found.

A

Non-motile

Found in food and water

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2
Q

Describe the critical inoculum of Shigella species.

A

Very low inoculum - <200 bacteria to cause infection

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3
Q

What do Shigella species cause?>

A

Bloody diarrhea, fever, cramps, dysentery

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4
Q

Where would you get Yersinia enterocolitica from?

A

Pork, cold cuts, water

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5
Q

What does Yersinia enterocolitica cause?

A

Diarrhea and pseudoappendicitis syndrome

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6
Q

What is pseudoappendicitis?

A

Yersinia enterocolitica gets into the mesenteric lymph nodes and produces a painful lymphadenopathy which can mimick the presentation of appendicitis

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7
Q

What is the bacterium that caused the black death?

A

Yersinia pestis

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8
Q

What are the two forms of the plague?

A

Bubonic and pneumonic forms

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9
Q

Where does one get yersinia pestis from?

A

Fleas from rats

carried by ground squirrels in the SW USA

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10
Q

What does bubos mean?

A

Lymph nodes of the groin

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11
Q

If someone has the pneumonic form, how can it be transmitted?

A

Via the respiratory route

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12
Q

How does one get the pneumonic form of the plague?

A

Lymph system is connected to the circulation via the thoracic duct which can allow Yersinia pestis to settle in the lungs

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13
Q

What is arteritis obliterans?

A

end of extremities mummify - blackening of extremities associated with the Black death

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14
Q

Describe the movement status of Klebsiella pneumoniae and what is causes.

A

Non motile

Pneumonia, UTIs, sepsis

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15
Q

Klebsiella pneumoniae causes pneumonia mostly in what individuals?

A

Alcoholics, the debilitated and the hospitalized

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16
Q

What does Klebsiella granulomatis cause?

A

Causes granuloma inguinale, an STI

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17
Q

Painless genital ulcers that look like primary syphilis but little inguinal lymphadenopathy.

A

Granuloma inguinale

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18
Q

Klebsiella granulomatis is more common where?

A

Developing countries

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19
Q

This bacterium is a leading cause of nosocomial infections.

A

Serratia marcescens

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20
Q

Very antibiotic resistant bacterium.

A

Serratia marcescens

21
Q

Some strains of this bacterium produce what type of pigment?

A

Blood red pigment (Serratia marcescens)

22
Q

When people get pneumonia at the ICU - these bacterial causes are the ones to worry about.

A

P. aeruginosa

Serratia marcesens

23
Q

How are non-fermenters different from the enterobacteriaceae?

A

they cannot ferment glucose

24
Q

How are non-fermenters distinguished from Enterobacteriaceae?

A

Non-fermenters fail to acidify the butt of a TSI agar or Kliger;s iron agar

25
What is tough about non-fermenters?
Tough to treat and identify
26
Non-fermenters constitute what percentage of gram negative isolates?
15%
27
What is a key characteristics of non-fermenters in terms of treatment?
Very antibiotic resistant - require longer courses of antibiotics then fermentative bacteria
28
75% of non-fermenting gram negative rod isolates belong to what three species?
P. aeruginosa Acinetobacter anitratus Stenotrophomonas maltophilia
29
Where can P. aeruginosa be found?
anywhere that is moist
30
What makes Pseudomonas aeruginosa able to tolerate many conditions?
Can live anywhere that is moist has minimal nutritional requirements Encapsulated Antibiotic resistant
31
Describe Pseudomonas aeruginosa's motility.
Polar flagella
32
What shaped colonies does Pseudomonas aeruginosa produce on MacKonkey agar?
football shaped colonies
33
What biochemical test could be used to differentiate between P. aeruginosa and A. anitratus + S. maltophilia?
P. aeruginosa is cytochrome oxidase positive, the others are not
34
What characteristic odour does Pseudomonas have?
Grape-like odour
35
Why are colonies usually seen as green?
Pyocyanin and pyoverdin pigments (blue and yellow, respectively) combine to form green
36
Surprisingly, what can P. aeruginosa contaminate?
Sterile solutions and even disinfectants
37
Pseudomonas infections are mostly of what type?
Nosocomial
38
P. aeruginosa is very invasive, how does it travel?
Along blood vessel walls.
39
Black coloured cellulitis that spreads fast along blood vessels.
Ecthyma gangrenosum
40
What are the different nosocomial infections caused by P. aeruginosa?
Pneumonia, UTIs, surgical wound infections, infectious of burns ecthyma gangrenosum
41
What are the different community acquired infections due to P. aeruginosa?
Malignant otitis externa (glue ear) Hot tub folliculitis Endocarditis Osteomyelitis of calcaneum
42
Endocarditis due to P. aeruginosa occurs in what people?
IV drug abusers
43
Malignant otitis externa mainly occurs to which individuals?
Type 1 diabetics
44
Osteomyelitis of calcaneum usually occurs after what type of injury?
Penetrating injury
45
Similarly to P. aeruginosa, Acinetobacter species can also contaminate what?
sterile solutions and even disinfectants
46
Stenotrophomas maltophilia tends to be isolated from what types of people?
Those on broad spectrum antibiotics - especially carbapenems
47
If this bacterium is overgrowing in the ICU, it indicates that carbapenem antibiotics are being overused.
Stenotrophomas maltophilia
48
This bacterium caused the closure of CF camps.
Burkoldaria cepacia (very resistant strains being passed on)
49
What does Burkoldaria cepacia cause?
Respiratory infections in CF patients.