Gram Negativ Organisms Flashcards
Where is enterobacter is normally found?
Normal flora of the digestive system
What shape and gram is enterobacter?
G (-) rods
Is enterobacter anaerobic, facultative, or aerobic?
Facultative anaerobes
What does enterohenorrhagic e. Coli do?
Has fimbrae that attach to human intestines and produce a toxin that causes hemorrhagic colitis
What are three symptoms of hemorrhagic colitis?
Bleeding, diarrhea, hemolytic uremia syndrome
Where does enterohenorrhagic E. coli come from? 3
Meat, unpasteurized juices, alfalfa sprouts
What is enterotoxigenic E. coli and what does it produce? 4
Enterotoxin that produces water diarrhea, vomiting, fever, and dehydration
What causes travelers diarrhea?
Enterotoxigenic E. coli
What are two diseases caused by salmonella?
Salmonellosis and salmonella gastroenteritis
What are the two major infectious groups of salmonella?
Septic and enteric
What is septic salmonella? 4
Invasive, high mortality rate, caused by s. Typhumurium/Dublin
What is enteric salmonellosis?
Effect intestinal tract, causing diarrhea and dehydration
What are antibiotics not very effective against and treatment consists if oral rehydration?
Salmonella
What are 5 ways to get salmonella?
Poultry, eggs, reptiles, vegtables, peanut butter
What does salmonella typhi cause?
Typhoid fever
How would you treat salmonella typhi?
Antibiotics
What are 5 symptoms of salmonella?
104 fever, ulcerative liesions of lymphoid tissues lining small intestine, abdominal tenderness, diarrhea, vomiting
What is klebsiella? Gram and shape
G(-) rod
What are three things k. Pneumoniae can cause?
Pneumonia, mastitis, septicemia
What does shigella flexneri cause?
Severe intestinal infections in primates
Where can you find serratia?
Soil
What are three symptoms of serratia?
Pneumonia, septicemia, mastitis
What shape and gram is pseudomonas?
G(-) rod
Is pseudomonas aerobic, anaerobic, or facultative?
Aerobic
Where is pseudomonas found?
Water and soil
Why is pseudomonas aeriginosa hard to get rid of?
Can use anything for its carbon source
What is pseudomonas dermatitis?
Self limiting rash that lasts two weeks
Where is pseudomonas dermatitis often found?
Swimming pools
What is Otis externa?
Painful chronic external ear canal infection
What causes Otis externa?
Pseudomonas aeriginosa
Who can pseudomonas aeriginosa seriously effect?
Burn patients
What has some treatment effect against pseudomonas aeriginosa?
Fluroquinolones
Is brucella positive or negative rod or cocci?
Negative rod
Is brucella motile or not?
No
How does brucella abortus travel? 2
Via the blood stream and lymphatic system
Where does brucella like to grow?
Intracellular
What does brucella abortus effect?
Livestock
What are three reservoirs for brucella?
Wild elk, bison, and dogs
Which disease has been virtually eliminated from the US?
Brucella abortus
What are three symptoms of brucellosis?
Undulant fever, chills, malaise
How can brucella abortus be transmitted?
Unpasteurized milk
How does brucella abortus enter he body?
Abrasions and mucous membranes
What happens once brucella abortus is in the body?
Ingested by macrophages and travels via circulatory system
What is the treatment for brucellosis abortus?
Tetracycline/streptomycin
What does vibrio cholerae look like? Gram and shape
Slightly curved gram negative rod
What is cholerae reservoir?
Shellfish
Where does cholera come from?
Food or water borne
How can cholera be spread?
Fecal contamination
What bacteria adheres to the intestinal lining without invading the cells?
Cholera
What does cholera produce?
Coleragen
What does coleragen do?
Stimulates GI epithelial cells to hyper secrete water and chloride ions
What are three symptoms of coleragen/cholera
Severe dehydration, profuse diarrhea, increased TP
How much water can you loose from cholera?
10-15 liters
What is the drug of choice for cholera?
Tetracycline
If left untreated how fatal is cholera?
50%
How fatal is it if treated?
15%
What does francisella tularensis cause?
Tularemia
What is francisella tularensis? positive, negative, aerobic, anaerobic, facultative anaerobic and shape?
Small, facultative anaerobe, pleomorphic
Is tularemia productive or negative?
Negative rod
When is tularemia most commonly aquired?
Skin breaks, inhalation, ingestion
What are three symptoms if tulerimia?
Localized infection, enlarged lymph nodes, filled with pus, septicemia, pneumonia, abscesses
What happens once people are exposed naturally to tularemia and recovered?
Perminently immunity
What are the two drugs of choice for tularemia?
Streptomycin or gentamicin
What is pasteurellosis multicoda?
G(-) rod
What animals can harbor pasteurellosis multicoda?
wild and domesticated
What does pasteurellosis multocida cause?
Septicemia
How is pasteurellosis transmitted?
Animal bites
What are four symptoms of pasteurellosis?
Localized with severe swelling and pains with acute onset
What are the two drug of choice for pasteurellosis?
Penicillin and tetracycline
What bacteria causes cat scratch fever?
Bartonella henselae
What is bartonella hensalae? E
Aerobic, gram - rod
Where is bartonella henselae normally found?
On cats and in their saliva
What are four symptoms of cat scratch fever?
Swollen lymph nodes, malaise, fever, endocarditis
What is the most common cause of diarrheal illness in the Us?
Campylobacter jejune
How is campylobacter spread?
Transmitted via contaminated food or water, or milk
What is leptospirosis interrorgans?
G(-) spirochete
What are 3 symptoms your animal has leptospirosis?
Fever, icterus, infertility, abortion
How is leptospirosis contracted?
Skin abrasion, mucous membranes with urine, water, soil, plants
What are two ways to treat leptospirosis?
Doxycycline or penicillin (May need IV)
What does borrelia burgdorferi cause?
G(-) sporochete
What are the two spirochete organisms?
Lepto and borrelia
What is the borrelia burgdorferi reservoir?
Wildlife
What is the borrelia burgdorferi vector?
Tick
What are five symptoms of animals with borrelia burgdorferi?
Fever, anorexia, swollen lymph nodes, lameness, fatigue
How can you prevent Lyme disease?
Tick control, insect repellent, keep shrubs away from the house, protective clothing
What does yersina pestis cause?
Bubonic plague
What does the bubonic plague look like?
Gram negative rod facultative anaerobe
What is the plagues reservoir?
Rodents
What is the plagues vector?
Flea