Glycolysis

Question 1

First step enzyme

Answer 1

Hexokinase

Question 2

First step reactant and product

Answer 2

Glucose —- glucose 6 phosphate

Question 3

2nd step enzyme

Answer 3

Phosphoglucose isomerase

Question 4

2nd step product and reactant

Answer 4

Glucose 6 phosphate —- fructose 6 phosphate

Question 5

3rd step enzyme

Answer 5

PFK

Phosphofructokinase

Question 6

3rd step reactant and product

Answer 6

Fructose 6 phosphate —- fructose 1,6 bisphospate

Question 7

Irreversible steps in glycolysis

Answer 7

1
3
10

Question 8

Rate limiting step in glycolysis

Answer 8

Step 3

PFK1

Question 9

In first half of glycolysis, ATP is used in steps ___ and ___

Answer 9

1

3

Question 10

Step 4 enzyme

Answer 10

Aldolase

Question 11

Step 4 reactant and product

Answer 11

Fructose 1,6 bisphosphate —- glyceraldehyde 3 phosphate and dihydroxyacetone phosphate

Question 12

Step 5 enzyme

Answer 12

Triose phosphate isomerase

Question 13

Step 5 reactant and product

Answer 13

Dihydroxyacetone phosphate —- glyceraldehyde 3 phosphate

Question 14

One glucose yields ___ pyruvates

Answer 14

2

Question 15

In second half of glycolysis, all reactions happen ___ times

Answer 15

2

Question 16

Step 6 enzyme

Answer 16

G3P dehydrogenase

Question 17

Step 6 reactant and product

Answer 17

Glyceraldehyde 3 phosphate

1, 3 Bisphosphoglycerate

Question 18

Step 7 enzyme

Answer 18

Phosphoglycerate kinase

Question 19

Step 7 reactant and product

Answer 19

1, 3 bisphosphoglycerate

3-phosphoglycerate

Question 20

Step 8 enzyme

Answer 20

Phosphoglycerate mutase

Question 21

Step 8 reactant and product

Answer 21

3- phosphoglycerate

2-phosphoglycerate

Question 22

Step 9 enzyme

Answer 22

Enolase

Question 23

Step 9 reactant and product

Answer 23

2- phosphoglycerate

Phosphoenolpyruvate

Question 24

Step 10 enzyme

Answer 24

Pyruvate kinase

Question 25

Step 10 reactant and product

Answer 25

Phosphoenolpyruvate

Pyruvate

Question 26

ATP used in steps __ and second half of glycolysis

Answer 26

7

10

Question 27

NAD+ reduced to NADH in step ___

Answer 27

6 ( G3P dehydrogenase)

Question 28

Water released in step

Answer 28

9 (dehydration via enolase)

Question 29

Other sugars that can enter glycolysis

Answer 29

Sucrose (glucose + fructose)

Lactose (glucose + galactose)

Question 30

Fructose enters glycolysis as

Answer 30

DHAP
Glyceraldehyde 3 phosphate
Hexokinase can convert fructose to fructose6-P

Question 31

Galactose enters glycolysis as

Answer 31

Glucose 6 phosphate

Question 32

Key enzymes of glycolysis

Answer 32

Hexokinase
PFK
Pyruvate kinase

Question 33

Inhibitors of PFK1

Answer 33

ATP
Low pH
Citrate

Question 34

Inhibition of PFK inhibits

Answer 34

Hexokinase

Question 35

Hexokinase in liver and beta cells of pancreas

Answer 35

Glucokinase

Question 36

Pyruvate kinase stimulated by

Answer 36

Fructose 1,6 phosphate

Question 37

Alanine inhibits

Answer 37

Pyruvate kinase

Question 38

Glucagon

Answer 38

Hormone secreted by pancreas when blood glucose is low

Question 39

Glucagon objective

Answer 39

Elevate blood glucose

Inhibit glycolysis
Inhibit glycogen synthesis

Question 40

What does PKA do in the liver?

Answer 40

Activates release of glucose from glycogen

Inhibit pyruvate kinase

Phosphorylates PFK2

Question 41

No receptors for glucagon on

Answer 41

Muscle

Question 42

When PFK2 kinase not phosphorylated, it

Answer 42

Catalyzes reaction fructose 6 phosphate into fructose 2,6 bisphosphate

Question 43

When PFK2 is phosphorylated, it catalyzes reaction

Answer 43

Fructose 2,6 bisphosphate into fructose 6 phosphate

Question 44

__ is a strong activator of PFK1

Answer 44

Fructose 2,6 bisphosphate

Question 45

When glucagon present, there is ___ and ___ is inhibited

Answer 45

Less fructose 2,6 bisphosphate

PFK1