Exam 3: Nucleotides And Nucleic Acids Flashcards
1
Q
Committed step in purine synthesis
A
PRPP to 5 phosphoribosylamine
GPAT
2
Q
Source of ribose 5 phosphate for nucleotide synthesis
A
PPP
3
Q
2 time methyl donor during purine synthesis
A
THF
4
Q
Nucleoside
A
Base + sugar
5
Q
Nucleotide
A
Base + sugar + phosphate
6
Q
Purines
A
G
A
7
Q
Pyrimidines
A
T
C
U
8
Q
Nucleotides made 2 ways
A
De novo synthesis
Salvage
9
Q
Salvage is preferred because
A
Less ATP is needed
10
Q
3 things needed for de novo synthesis
A
ATP
Ribose 5 phosphate
PRPP
11
Q
___ used in both purine and pyrimidine synthesis
A
PRPP
12
Q
PRPP synthetase reaction
A
Ribose 5P —> PRPP
13
Q
GPAT reaction
A
PRPP —> 5 phosphoribosylamine
14
Q
Steps using ATP in purine synthesis
A
3, 5, 6
15
Q
Steps adding C’s in purine synthesis
A
4, 7
