Exam 3: Nitrogen Excretion Flashcards
1
Q
__ cannot be stored in body
A
Nitrogen
2
Q
Transamination results in __ and ___ (AA transfer alpha amino group to alpha ketoglutarate)
A
Glutamate
Alpha keto acid
3
Q
Entry points in urea cycle
A
GDH (glutamate DH)
AST (aspartate aminotransferase)
4
Q
Key liver enzymes
A
AST
ALT
5
Q
Unique abilities of liver
A
Urea cycle
GNG
6
Q
Source of N for urea formation
A
Glutamate
7
Q
Enzyme involved in formation of carbamoyl phosphate
A
CPS
8
Q
Strong allosteric activator of CPS
A
N-acetylglutamate
9
Q
OAA to aspartate
A
AST
10
Q
Fate of muscle alanine
A
Pyruvate
Acetyl CoA
Glucose
CO2
11
Q
Glutamate to alpha ketoglutarate
A
GDH
12
Q
L-citrulline is shipped to cytosol from
A
Mitochondrial matrix
13
Q
Rate limiting step in urea cycle
A
CPS 1
14
Q
In urea, one N comes from ___ and one comes from ___
A
Aspartate
Free NH3
