Exam 3: AA Metabolism Flashcards

1
Q

AA metabolism occurs in

A

Muscle

Liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

____ are absorbed faster than smaller AA

A

BCAA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

___ and ___ absorption is more efficient than free AA absorption

A

Di- and tri-peptide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Once in enterocyte, peptides broken down into

A

Free AA for the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Low energy charge:

AA is….

A

Oxidized to recreate ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Low glucose:

AA is…

A

Sent to liver to turn into glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

High energy charge and lots of glucose:

AA is…

A

Sent to liver and turned into fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

AA may also be used to synthesize

A

Protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Alpha AA can be broken down to

A

Amino group

Carbon skeleton (alpha keto acid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ketoacids can be used to make

A

ATP
CO2
Glucose
Fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What happens to an alpha ketoacid depends on

A

Energy charge
Hormones
Glucose concentration
Tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Liver can oxidize

A

Most of the 20 AA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Muscle can only oxidize

A

LIVGAA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Alanine alpha ketoacid

A

Pyruvate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Glutamine/glutamate alpha ketoacid

A

Alpha ketoglutarate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Asparagine/aspartate alpha ketoacid

17
Q

2 AA that cannot turn into glucose

A

Leucine

Lysine

18
Q

BCAAs

19
Q

Exercise creates ___ in muscle

A

Low energy charge

20
Q

Exercise uses the ___ cycle to release glucose into the blood

A

Glucose alanine cycle

21
Q

Pyruvate —-> alanine catalyzed by

A

Alanine transaminase (ALT)

22
Q

Pyruvate cleared in the liver by ___ in GNG

A

Pyruvate carboxylase

23
Q

___ maintainers blood glucose during exercise

A

Glucose alanine cycle

24
Q

Carbons in alanine came from

A

Muscle glycogen

25
Alanine may provide __ energy during exercise
5%
26
Low intensity exercise: No change in ___ 20% decrease in ___
Skeletal muscle alanine concentration Skeletal muscle glutamate concentration
27
Moderate exercise: 40% decreases in ___ Increase in ___
Skeletal muscle glutamate concentration Alanine concentration
28
Glutamine glutamate cycle is used to
Export Nitrogen from muscle to the liver, GI, and immune system
29
___ adds nitrogen to glutamate to create glutamine
Glutamine synthetase
30
___ hydrolyzes glutamine into glutamate
Glutaminase
31
Most AA are released in direct proportion to relative occurrence in muscle protein EXCEPT
LIVGAA Glutamine Alanine
32
Alanine and glutamine released ___ than taken in
More
33
Alanine and glutamine are the most ____ ____ AA
Abundantly released
34
LIVGAA are released ___ than taken in
Less
35
Contains 2 Amino groups
Glutamine
36
Glucogenic and ketogenic
PITT (sometimes threonine)
37
Primarily exported by muscle
Alanine | Glutamine
38
During exercise, muscle takes in ___ and releases __
Glutamate Alanine
39
Muscle often uses this AA for nitrogen donation
Glutamine