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Year 1 Core Drugs List > GI- proton pump inhibitor > Flashcards

GI- proton pump inhibitor Flashcards

1
Q

PPI examples

A

Lansoprazole, omeprazole

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2
Q

PPI indications

A

GORD, Barrett’s oesophagus, gastric and duodenal ulcers

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3
Q

PPI moa

A

To decrease hydrochloric acid secretion in stomach normally via hydrogen-potassium ATPase pump on parietal cell membrane, PPI’s bind to and irreversibly inhibit the pump limiting secretion, reducing acid conc.

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4
Q

PPI side effects

A

hypomagnesaemia, increased risk of fractures, jaundice, rash, B12 deficiency, stomach cancer

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5
Q

PPI cautions

A

alcohol

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Year 1 Core Drugs List (26 decks)

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