Cardiac Drugs- Aspirin

Question 1

Aspirin indications

Answer 1

peripheral arterial disease, post-stroke, post-MI

Question 2

Aspirin MOA

Answer 2

Platelets help blood clots stick. Thromboxane A2 important for platelet aggregation cant be produced as COX-1 is inhibited so platelet aggregation can’t occur

Question 3

Aspirin side effects

Answer 3

Potential severe bleeds (GI) more likely if ulcer present. Bleeding may lead to stroke

Question 4

Aspirin cautions

Answer 4

Asthmatics, clotting disorders, stomach ulcer (cause/worsen)