Cardiac Drugs- CCB

Question 1

CCB Examples

Answer 1

Amlodipine Verapamil Diltiazem

Question 2

CCB non-dihydropyridines acts on

Answer 2

heart>vessels

Question 3

CCB non-dihydropyridines MOA

Answer 3

inhibition of SA/AV nodes slowing cardiac contractions
by blocking the calcium channels present in the heart muscle and reduce the influx of calcium into cardiac muscle cells (myocytes)

Question 4

CCB non-dihydropyridines example

Answer 4

Verapamil

Question 5

CCB dihydropyridines acts on

Answer 5

Vessels>heart

Question 6

CCB dihydropyridines MOA

Answer 6

peripheral vasodilators (expands vessels)
By binding to and blocking voltage-gated L-type calcium channels found on smooth muscle cells of arterial blood vessels

Question 7

CCB dihydropyridines example

Answer 7

amlodipine (-pine suffix)

Question 8

CCB main indications

Answer 8

Angina, abnormal heart rhythms, hypertension

Question 9

CCB side-effects

Answer 9

lightheadedness, bradycardia, hypotension, peripheral oedema

Question 10

CCB cautions

Answer 10

No grapefruit, no bradycardic or renal/hepatic impaired patients. CI with digoxin