GI-H2-receptor antagonists

Question 1

H2-receptor antagonists indications

Answer 1

heart burn, acid reflux, GORD, peptic ulcer disease

Question 2

H2-receptor antagonists examples

Answer 2

(-tidine) cimetidine, famotidine

Question 3

H2-receptor antagonists moa

Answer 3

H2-receptor antagonists reduces the secretion of gastric acid by reversible binding to histamine (H2) receptors, which are found on gastric parietal cells. This process leads to the inhibition of histamine binding to this receptor, causing the reduction of gastric acid secretion.

Question 4

H2-receptor antagonists side effects

Answer 4

jaundice, fever/chills, hair/skin problems, easy bruising/bleeding, potential increased cancer risk

Question 5

H2-receptor antagonists cautions

Answer 5

ranitidine increased cancer risk so taken off market