Cardiac Drugs- Loop Diuretics Flashcards
LD examples
Furosemide, bumetanide
LD indications
fluid overload conditions e.g. heart failure, oedema, hypertension
LD MOA
Acts on the Loop on Henle in the kidneys help put extra salt and water into your urine. This is how diuretics clear extra fluid out and bring down your blood pressure. Diuretics also help when you have too much fluid collecting because of heart failure or other medical problems.
fluid in blood->kidneys->urine
lowering fluid in blood by inhibiting the Na-K-2Cl carrier in the luminal membrane!
LD side effects
Postural hypertension, gastrointestinal upset, hyponatremia, hypokalemia and dehydration
LD cautions
osteoprosis patients, must monitor blood pressures, fluid status (including weight), serum electrolytes, and renal function