CNS- Codeine Flashcards
1
Q
Codeine indications
A
Persistant, diarrhea, pain,
2
Q
Codeine MOA
A
Opioid receptors (codeine is an opioid) are all g-coupled protein receptors
When opioids bind to these receptors a decreased intracellular cAMP (messenger molecule), hyperpolarization of the cell and neuronal cells, and decreased neurotransmitter release.
3
Q
Codeine side effects
A
addictive, tiredness, muscle stiffness
4
Q
Codeine cautions
A
not for intestinal obstruction patients, or respiratory patients with shallow breathing
