CNS- paracetamol

Question 1

Paracetamol indications

Answer 1

mild/moderate pain e.g. headaches, sprains

Question 2

Paracetamol MOA

Answer 2

Inhibits prostaglandin synthesis by blocking cox-1 and cox-2. Prostaglandins are secreted by body in response to pain sensitizing nerve endings to pain increasing bodys pain percetion (the body becomes sensitive to pain) and also promotes inflammatory response.

Question 3

Paracetamol side effects

Answer 3

low BP, low platelets/wbc

Question 4

Paracetamol cautions

Answer 4

if underweight, have alcohol ‘issues’, liver/kidney problems