Cardiac Drugs- ACEi

Question 1

ACEi examples

Answer 1

ramipril, lisinopril, perindopril -pril

Question 1

ACEi indications

Answer 1

hypertension, post MI, heart failure

Question 2

ACEi MOA

Answer 2

2. produce vasodilation by inhibiting synthesis of angiotensin 2 (from 1)

angiotensin 1——>(via ACE) angiotensin 2 (which would normally cause increased blood pressure)

Question 3

ACEi side effects

Answer 3

dry cough

Question 4

ACEi cautions

Answer 4

less effective in black afro-caribbean, those taking diuretics, certain stenosis