Genomes Flashcards

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1
Q

What are the goals of the HGP?

A
  • To sequence the human genome
  • To identify genes and their functions
  • To investigate the associations between genes and disease
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2
Q

How many genes in the human genome?

What % of these are coding ones?

A

21,000

1.6%

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3
Q

Give the name of some sequences in DNA

A

Introns
Protein-coding regions
Non-repetitive and non coding DNA
Repeated sequences (LINES and SINES - long and short interspersed elements)

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4
Q

What is bioinformatics?

A

Using computers to analyse and organise genome data

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5
Q

What does comparison of known genes help us to do?

What does comparison of predicted amino acid sequence and 3D structures help us to do?

A

To identify genes and suggest functions

Helps assign proteins to functional families

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6
Q

What other ‘omes’ are we now studying?

A

The transcriptome
The proteome
The microbiome

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7
Q

What are common differences between organisms called?

A

Polymorphisms

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8
Q

What is the most common type of human polymorphism?

A

Single nucleotide polymorphisms

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9
Q

Which feature of the human genome is derived from insertion of retro virus genomes?

A

LINEs (long intersperses elements)

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