Genomes Flashcards
TRUE OR FALSE - ALL somatic cells contain the same genome
TRUE
What do transcriptomes code for?
RNA
What do proteosomes code for?
Proteins
Describe the genome of E.Coli?
single circular chromosomal DNA molecule contains the genome
How is the genome of E.Coli replicated?
Bi-directional
Where are house keeping genes expressed?
ALL cell types
What cells are diploid in eukaryotic cells?
ALL cells except germ cells
What is the centromere?
specialised repetitive DNA sequences
What is the centromere attached to?
kinetochore
What is the replication origin?
DNA sequence where DNA replication is initiated
What is the telomere?
Specialised DNA sequences at the end of linear chromosomes
What is the function of the telomere?
Maintain chromosomal integrity
Which enzyme maintains the telomere?
Enzyme telomerase
Describe the correlation between organism and genomes
As organism complexity increases, genome size increases
Describe the correlation between gene density and organism complexity
As organism complexity increases, gene density declines
What do larger genes contain more of?
Repetitive DNA elements like transposons and retrotransposons
Describe the characteristics of larger genomes
Contain more complex transcriptional control elements distributed over larger regions of DNA E.G. promoters & enhancers
what contains the protein-coding sequences in eukaryotic genes?
Exons
What are retrotransposons?
genetic elements that amplify themselves in the genome