Connective Tissue Flashcards
What are the types of connective tissue
collagen, reticular, elastic
What forms the connective tissue
mesoderm
What are the functions of connective tissue
energy storage, repair, transport, protection
What is the function of collagen fibres
provide cushioning and strength
Describe dermis
dense and irregular
Describe type 1 collagen
large branched fibres
Describe type 4 collagen
forms sheets - basement membrane
Describe type 7 collagen
short fibrils
What is the function of type 7 collagen
anchor cells to BM
What is collagen made by
fibroblasts
What amino acids is collagen rich in
glycine and proline
Where is reticular tissue found
lymph nodes and bone marrow
What is reticular tissue formed from
short reticular fibres
What does reticular tissue produce
short fibres of collagen, scaffolding
What do reticular cells make
reticular fibres
Describe the appearance of elastic fibres
yellow and thin
What do elastic fibres produce
elastic tissues
What are elastic fibres
bundles of proteins
Where are elastic fibres found
extracellular matrix
What produces elastic fibres
fibroblasts, smooth muscle cells
What do elastic fibres allow
stretch and recoil
What are some examples of connective tissue cells
mast cells, macrophages, chondrocytes, plasma cells
What is the active form of connective tissue cells
fibroblasts
What is the inactive form of connective tissue cells
fibrocytes
Describe fibroblasts
round nuclei, euchromatic, light stain
Describe fibrocytes
flat heterochromic nucleus, dark stain, little cytoplasm
What are adipocytes
fat cells
Describe white fat cells
unilocular, one large fat droplet
Describe brown fat cels
multilocular, small droplets
Which fat cell is metabolically active
brown fat cells
What do adipocytes contain
lots of smooth ER, pinocytic vesicles
What is the fucntion of type 3 collagen
protective sleeve
What is the function of adipocytes
receptor for insulin, thyroid hormones
What does the ECM retain
water, sodium, positive ions
Describe the ECM charge
highly negative
What do proteoglycans allow
selective diffusion
What are the types of GAGs
hyaluronic acid, chrondroitin sulphate, hepapran sulphate
Where are hepapran sulphates found
lung, basement membrane, liver
Where are keratan sulphates found
cartilage, intervertebral discs