Cell cycle Flashcards
What are the phases of the cell cycle
G1, S, G2 and M
Describe the characteristics of G1 phase
cell size maintained, nutritional control, variable length
What happens in S phase
DNA replication
Describe the characteristics of g2 phase
Growth, DNA has been replicated, centrosomes have been duplicated
How can you detect what phase of the cell cycle a cell is in
fluorescent DNA dyes determine DNA content in cells
How long is M phase
less than 1 hour in humans
What stage of M phase can cells pause
metaphase
What is the mitotic spindle comprised of
centrosomes, spindle microtubules and asters
What is the function of the mitotic spindle?
segregates chromosomes into daughter cells
What is the aster
radial array of short microtubules
what is the kinetochore?
large protein complexes
where does the kinetochore assemble
chromosomes and centromeres
What is the function of the kinetochore?
mediate attachment of mitotic spindle to microtubules
What are the different types of microtubules
astral microtubules, kinetochore microtubules, inter-polar microtubules
Which microtubules are structural
inter polar and astral