genetic disorders/diseases (f) Flashcards
what are the three main types of disorders
gene, chromosome, and inherited through body cell mutation
gene mutation
affecting the DNA sequence
chromosome mutation
changing the number or location of genes
inherited through body cell
autosomal or sex cell
what are the three types of inherited disorders
autosomal dominant, autosomal recessive, x-linked recessive
autosomal dominant
expressed with one copy of the dominant allele, only in body cells
autosomal recessive
expressed with two copies of the recessive allele, only in body cells
x-linked recessive
expressed with one (male) or 2 (female) copies of the recessive allele, only in reproduction cells
occurs during DNA replication
a change to the original DNA sequence
examples that occur during dna replication
cystic fibrosis, sickle cell anemia
occurs during meiosis
exchanges the number or location of genes on the chromosome