dna replication (f) Flashcards

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1
Q

what is dna

A

double stranded, antiparallel, a double helix, and is made of nucleotides

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2
Q

double stranded

A

complementary strands

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3
Q

antiparallel

A

runs in opposite directions

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4
Q

double helix

A

two backbones to the helix

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5
Q

made of nucleotides

A

adenine thymine guanine cytosine

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6
Q

what are the parts of a nucleotide

A

nitrogen base, phosphate, and sugar

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7
Q

sugar also known as

A

deoxyribose

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8
Q

nitrogen base

A

makes nucleotides different from one anoter

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9
Q

what are the enzymes involved in dna repliaction

A

primase, polymerase, ligase, helicase

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10
Q

primase

A

starts dna synthesis

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11
Q

dna polymerase

A

adds dna bases and proofreads the strand

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12
Q

dna ligase

A

seals gaps in dna by connecting dna segments

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13
Q

helicase

A

opens the two strands of dna, creates the origin of replication

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14
Q

leading strand

A

continous replication

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15
Q

lagging strand

A

discontinous replication

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16
Q

leading strand

A

made towards the replication fork

17
Q

how many primers do you need for leading strand

A

1

18
Q

continuous or discontinuous replication in leading strand?

A

continuous

19
Q

lagging strand

A

made away from the replication fork

20
Q

how many primers are needed for lagging strand

A

many

21
Q

continuous or discontinuous replication in lagging strand?

A

discontinuous, creates okazaki fragments

22
Q

how many steps are in dna replication

A

4

23
Q

first step of dna replication

A

Helicase opens the helix, creating the origin of replication

24
Q

second step of dna replication

A

Primase puts down a primer to tell Polymerase where to begin

25
Q

third step of dna replication

A

Polymerase puts down new base pairs, building the complementary strand

26
Q

fourth step of dna replication

A

Ligase binds all of the fragments of DNA together, to create a continuous strand

27
Q

nondisjunction

A

homologous chromosomes that failed to separate in meiosis

28
Q

what is the result in nondisjunction

A

trisomy or monosomy

29
Q

what is trisomy

A

three extra chromosomes

30
Q

what is monosomy

A

one extra chromosomes

31
Q

xy

A

male

32
Q

xx

A

female

33
Q

karyotype

A

a visual to show a complete set of chromosomes

34
Q

when does dna replicate

A

right before it divides

35
Q

semi-conservative

A

two copies contain one old original strand and one new strand

36
Q

5’ -> 3’

A

dna polymerase always builds in this direction

37
Q

antiparallel (5’ -> 3’)

A

dna strands run in opposite direction, one goes in the 5 -> 3 direction while the other goes in the 3’ -> 5’ direction

38
Q

prime

A

the carbons on the nitrogen base are numbered

the apostrophes are called prime

39
Q

what direction are leading and lagging strand in

A

5’ -> 3’’