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Neuroscience (1206) > Genesis of Nerve Membrane Potential > Flashcards

Genesis of Nerve Membrane Potential Flashcards

1
Q

What is the resting membrane potential in nerve cells

A

-70mV

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2
Q

what is the resting membrane potential in cardiac and skeletal cells

A

-85mV to -90mV

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3
Q

What do all excitable tissues have

A

RMP

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4
Q

What is the average extracellular Na+ ion concentration

A

140mEq/L

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5
Q

What is the average extracellular K+ ion concentration

A

4mEq/L

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6
Q

What is the average extracellular Cl- ion concentration

A

125mEq/L

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7
Q

What is the average intracellular Na+ ion concentration

A

14mEq/L

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8
Q

What is the average intracellular K+ ion concentration

A

140mEq/L

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9
Q

What is the average intracellular Cl- ion concentration

A

9mEq/L

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10
Q

What causes the genesis of RMP in nerve cells

A 
Non- diffusable proteins, uneven distribution of K+, Na+, Cl- and 
transport Proteins (Na/K pump, K+ leaky channel)
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11
Q

When 3___ flows out of the electrogenic pump, 2___ flows through the electrogenic pump

A

Na+, K+

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12
Q

What two forces help to regulate the movement of ions in and out of the cell

A

Diffusion forces, Electrostatic Forces

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13
Q

True or false, K+ ions are permeable to the cell membrane

A

True

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14
Q

True or False, Na+ ions are permeable to the cell membrane

A

False

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15
Q

True or False, Cl- ions are semi permeable to the cell membrane

A

True

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16
Q

Term given when the membrane potential at which the tendency to move against the electrical or concentration gradient is exactly balanced

A

Equilibrium Potential

17
Q

What are the 3 assumptions of Nernst Equation

A

Membrane is selectively and totally permeable to each ion

Each ion is in electrochemical equilibrium across the membrane

Diffusing ion is isolated from all other ions

18
Q

Term given to a decrease in Vm which results in nerve excitability

A

Hyperkelemia

Neuroscience (1206) (17 decks)

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