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Neuroscience (1206) > Differences between Autonomic and Somatic Systems > Flashcards

Differences between Autonomic and Somatic Systems Flashcards

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1
Q

What are the two systems of the peripheral N.S

A

Efferent System, Afferent System

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2
Q

What are the two types of Efferent System

A

Somatic NS, Autonomic NS

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3
Q

What are the muscles associated with Somatic NS

A

Skeletal muscles

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4
Q

What type of control is associated with the Somatic NS

A

Voluntary System

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5
Q

What tissues are associated with the ANS

A

Heart and smooth muscles, glands

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6
Q

What type of control is associated with the ANS

A

Involuntary System

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7
Q

What fibres are associated with the Somatic NS

A

A

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8
Q

What fibres are associated with the ANS

A

Preganglionic B, Postganglionic C

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9
Q

True or False ANS only excites tissue

A

False, it Excites and Inhibits

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10
Q

What is the name of the neurotransmitter blocker for nicotinic acetylcholinic receptors in the Somatic NS

A

d-Tubocurarine

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11
Q

What is the name of the receptors for ACH

A

Nicotinic receptors

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12
Q

What is the name of the neurotransmitter blocker for between the B and C receptors for the ANS

A

Hexamethonium

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13
Q

What is the name of the neurotransmitters in the ANS

A

Acetylcholine and Norepinephrine

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14
Q

What is the name of the receptor that Norepinephrine binds to

A

alpha, beta receptors

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15
Q

What is the name of the neurotransmitter that ACh binds itself to in the Somatic Nervous System

A

Muscarinic Receptors

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16
Q

When there are low concentrations of ACh, what is hormone is secreted

A

Nicotine

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17
Q

When there are high concentrations of ACh, what is hormone is secreted

A

Hexamethonium

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18
Q

What is the neurotransmitter blocker for muscarinic receptors

A

Atropine

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19
Q

What tissues do M1 receptors act on

A

Brain

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20
Q

What tissues do M2 receptors act on

A

Heart

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21
Q

What tissues do M3-M5 receptors act on

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A

Smooth muscles

22
Q

What another name for Nor- epinephrine

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A

Nor-Adrenaline

23
Q

What organ releases E, NE into the peripheral blood

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A

Adrenal Medulla

24
Q

What amino acid is NA synthesised from

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A

Phenylalanine, Tyrosine, DOPA, Dopamine

25
What is the precursor for Tyrosine
Phenylalanine
26
What is required for the storage of NA in vesicles
ATP and chromogranins
27
What two drugs interfere with the storage of NA
Reserpine, Guanethidine
28
What gland converts NA to Adrenaline
Adrenal Medulla
29
What two neurotransmitters bind to alpha and beta receptors | After binding what is activated to produce secondary messengers
NE and E | G-Proteins
30
What is used in the metabolism of NA
``` Catechol-O-methyltransferase Monoamine oxidase (MAO) ```
31
What is the precursor for DOPA
Tyrosine
32
What is the precursor for Dopamine
DOPA
33
What is the precursor for Nor-adrenaline
Dopamine
34
What does NE get broken down into, using the metabolite, Catechol-O-methyltransferase
Normetanephrine Homovanillic acid | VMA
35
What does NE get broken down into, using the metabolite Monoamine Oxidase (MOA)
3,4 Dihydroxy-mandelic aldehyde | Vanillylmandelic acid
36
What are normal plasma levels of NE
300 pg/ml | 1.8 nmol/L
37
What are normal plasma levels of E
30 pg/ml | 0.16 nmol/L
38
What are normal plasma levels of DA
35 pg/ml (0.23 nmol/L
39
True or False, Norepinephrine excites mainly alpha receptors but excites the beta receptors to a lesser extent
True
40
α1 and α2 receptors are located in which areas of the body
Smooth muscles, blood vessels
41
β1 receptors are located in which areas of the body
Heart | Adipose tissue, Juxtaglomerular apparatus
42
β2 receptors are located in which areas of the body
Lungs | Arterioles
43
β3 receptors are located in which areas of the body
Adipose tissues
44
True or false, in 2nd messenger mediated responses, α1 increases IP3 and DAG productions
True
45
True or False, in 2nd messenger mediated responses, α2 decrease cell action membrane potential
True
46
True or False, in 2nd messenger mediated responses, β1-β3 increases cell AMP
True
47
True or False, in 2nd messenger mediated responses, IP3 increases in M1,M3 and M5receptors
True
48
True or False, in 2nd messenger mediated responses, c AMP increases in M2 and M4 receptors
False, decrease
49
What fibres innervate Eccrine Sweat glands and some blood vessels in in the skeletal muscles
Cholinergic Sympathetic Fibres
50
True or False, All preganglionic autonomic fibres are cholinergic
True

Neuroscience (1206) (17 decks)

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