Functional Organization of the Nervous System

Question 1

The Nervous System is known as the _____ of the living organism

Answer 1

Integration Centre

Question 2

Principal functional units of the nervous system

Answer 2

Neurons

Question 3

True or False, Non-neuronal cells are more in numbers than Neurons

Answer 3

True

Question 4

What are the different type of Non-neuronal Cells

Answer 4

Astroglia, Microglia, Ependymal Cells, Oligodendrogliocytes

Question 5

What non-neuronal cell form the the Blood Brain Barrier

Answer 5

Astroglia

Question 6

What non-neuronal cell produces neurotrophins

Answer 6

Astroglia

Question 7

Neutrophins are responsible for what ?

Answer 7

Survival and Growth

Question 8

What non-neuronal cell form Myelin sheaths in the CNS

Answer 8

Oligodendrogliocytes

Question 9

Where do Oligiodendrogliocytes occupy 75% of

Answer 9

White Matter

Question 10

Microglia are what type of cells?

Answer 10

Phagocytic

Question 11

Where are Microglia scattered

Answer 11

Grey Matter

Question 12

Where are ependymal cells found

Answer 12

fluid-filled ventricles of the brain

Question 13

What non-neuronal cells functions to direct cell migration during brain development

Answer 13

Ependymal Cells

Question 14

What part of the neuron is a receptor zone, that contains spines. especially in the cerebral and cerebellar cortex

Answer 14

Dendrites

Question 15

What part of the neuron maintains the functional and anatomical integrity of the axon

Answer 15

Cell Body or Soma

Question 16

What does the cell body/stoma contain?/

Answer 16

Nissl Granules, Nucleus, neurofibrils

Question 17

What part of the neuron is the most excitable region

Answer 17

Axon Hillock

Question 18

What cells myelinate the axon the Peripheral Nervous system

Answer 18

Schwann cells

Question 19

Long, fibrous, myelinated region of the neuron

Answer 19

Axon

Question 20

End region of the neuron that is involved in neurotransmission

Answer 20

Telodendria or terminal buttons

Question 21

True or false, ribosomes synthesize proteins in axons

Answer 21

False, it’s the Soma

Question 22

The term given to the movement of proteins from the soma to the terminal endings

Answer 22

Anterograde transport

Question 23

The term given to the movement of proteins from the terminal endings to the some

Answer 23

Retrograde transport

Question 24

What is the name of the molecular motors that move ‘cargo’ along microtubles

Answer 24

Kinesin & Dyenin

Question 25

Most numerous non-neuronal cell

Answer 25

Astroglia

Question 26

What occurs with complete severance of the peripheral nerves ( (Wallerian & Regeneration))

Answer 26

Chromatolysis, Swelling of the Cell Body,

retention of nucleus (leads to regeneration)

Question 27

Term given to the degeneration of Nissl Granules

Answer 27

Chromatolysis

Question 28

How long does Chromatolyisis last

Answer 28

24hours

Question 29

True or False, if the nucleus is pushed out of the stoma, regeneration of the peripheral nerve can still occur

Answer 29

False

Question 30

What change in the axon occurs at the site of injury during severance (Wallerian & Regeneration)

Answer 30

Orthograde and Retrograde Degeneration

Question 31

Term given to the increased responsiveness of the end organs or muscles following injury (denervation) of the peripheral nerve

Answer 31

Denervation Super or Hyper- Sensitivity

Question 32

What are the processes that occur following nerve injury (Denervation Super or Hyper- Sensitivity)

Answer 32

Regenerative Sprouting, Lack of Re-uptake of neurotransmitters, Hyper-responsive to neurotransmitters, Up-regulation of receptors on effector tissue

Question 33

What is the release phenomenom

Answer 33

Term given when higher centers in the CNS causes activity in the lower centres to increase

Question 34

Many of the Signs of neurologic diseases is usually because of _________

Answer 34

Denervation Supersensitivity

Question 35

Name of the drug that is able to pass the BBB to treat Parkinsons disease

Answer 35

L- Dopa