General Anesthetics Flashcards
MOA of general anesthetics
- GABA agonism
- Na+ channel blockade
- Ca+ channel blockade
2 types of anesthetics
- Generalize anesthetics
- Local anesthetics
- HIGH blood/gas ratio =
- HIGH MAC =
- Slow onset/slow recovery
- Low Potency
General Anesthetics use for Asthmatics
Enflurane (or Isoflurane)
General Anesthetics use for Dental surgery
Nitrous Oxide
General Anesthetics use for Children
Desflurane or Sevoflurane
Dissociative anesthetic
Ketamine
Anterograde amnesia
Mizadolam (BZD)
No CV & lung depression
Etomidate
Default induction anesthetic
Propofol
what type of anesthetics are esters and amides
Local anesthetics
MOA of Local anesthetics
Na+ channel blockade
Only vasoconstrictor local anesthetics
Cocaine
1st LA
1st Natural: Cocaine
1st Synthetic: Procaine
Universal LA
Lidocaine
EMLA
Prilocaine + Lidocaine
Most widely used long-acting amide LA for labor and delivery
Bupivacaine