Autocoids*** Flashcards
1
Q
BESH
A
Bradykinin
Eicosanoid
Serotonin
Histamine
2
Q
histamine precursor
A
Hsitidine
3
Q
Serotonin precursor
A
Tryptophan
4
Q
Eicosanoid precursor
A
Arachidonic acid
5
Q
Aka β-hypophamine
A
Vasopressin/ADH
6
Q
Aka α-hypophamine
A
Oxytocin
7
Q
↑ bradykinin leads to
A
dry cough (ACEIs)
8
Q
Most potent constrictor
A
Endothelin
9
Q
What are the Serotonins
A
5-HT1b/1d
5HT2A
5-HT3
5-HT4
10
Q
Partial agonists: (-triptans)
Mgt. acute migraines
Triptans = migraines
A
5-HT1b/1d
11
Q
Blockers: atypical antipsychotics (OlanZAPINE)
A
5HT2A
12
Q
Effect: N & V
Blockers: (-setron)
A
5-HT3
13
Q
Effect: ↑ peristalsis
Agonist: Tegaserod (IBS-C)
A
5-HT4
14
Q
✓ Effects: vasodilation, edema, allergy
✓ Blockers: Diphenhydramine (Anti-histamine)
A
H1
15
Q
✓ Effect: ↑ acid secretion = ulcer
✓ Blockers: Cimetidine
A
H2
